Download RTMNU B.Pharma 4th Semester 2017 Summer Pharmaceutical Microbiology and Immunology 2 Question Paper

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B.Pharm. Semester—IV (C.B.S.) Examination

PHARMACEUTICAL MICROBIOLOGY AND IMMUNOLOGY-II

Paper-5

Time: Three Hours]

[Maximum Marks: 80

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N.B. :— (1) Question No. 1 is compulsory.

(2) Solve any FOUR questions from remaining.

(3) Draw neat labelled diagram wherever necessary.

1. Solve any five questions :
   1. Define D value and Z value.
   2. Give the factors affecting disinfectant action.

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   3. Differentiate between exotoxins and endotoxins.
   4. Differentiate between vaccines and sera.
   5. What are antigens ?
   6. Comment on sources of contamination in aseptic area and methods of prevention. 4×5=20

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2. Explain non-specific defense mechanisms of host. 15
3. Give the applications of antigen-antibody reactions. Explain the different types of antigen antibody reactions. 15
4. 1. Discuss the different types of hypersensitivity reactions. 8
   2. Define immunity. Describe the different types of immunity. 7

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5. 1. Explain the mechanism and process of moist heat sterilization. 8
   2. What are sterilization indicators ? Explain the different types of it. 7
6. 1. Explain the method of preparation of BCG vaccine or diphtheria toxoid. 8
   2. Describe the construction, working and applications of laminar air flow unit. 7

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7. Write short notes on any three :
   1. Sterility testing of pharmaceutical products as per I.P.
   2. Design of aseptic area
   3. Tuberculin test as diagnostic agent
   4. Classification of disinfectants and ideal properties of disinfectants. 3×5=15

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NXO-20311