Download RTMNU B.Pharma 4th Semester 2017 Winter Pharmaceutical Microbiology and Immunology 2 Question Paper

NRJ/KW/17/4277

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B.Pharm.

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PHARMACEUTICAL MICROBIOLOGY AND IMMUNOLOGY—II

Paper-5

Time: Three Hours] [Maximum Marks: 80

Note :- (1) Question No. 1 is compulsory.

(2) Solve any FOUR questions from remaining.

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(3) Draw neat labelled diagrams wherever necessary.

1. Solve any FIVE of the following :
   1. Explain in brief about sterilization indicators.
   2. Write the sources of contamination in aseptic area.
   3. Discuss about the portal of entry of Microorganism.
   4. Explain in detail about the structure of antibody and enlist its classes.

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   5. Write a note on ELISA.
   6. Define immunity and enlist the various types of immunity.
   7. Explain the various factors affecting disinfection activity.

   5×4=20

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2. Define sterilization and enlist the various methods of sterilization and elaborate the Moist heat sterilization.

   15

3. 1. Draw a neat, labelled, layout for designing the Aseptic area and elaborate its parts.

      8

   2. Explain the non specific defense mechanism.

      7

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4. 1. Define disinfectants and classify.

      8

   2. Discuss the method of preparation of diphtheria.

      7

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5. 1. Discuss in detail about Antigen, Antibodies reaction.

      10

   2. Write note on radioimmunoassay.

      5

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6. Differentiate the following :
   1. Vaccines and Sera
   2. Antigen and antibody
   3. Exotoxins and Endotoxins.

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7. Write short notes on (any THREE):
   1. Diagnostic Agents
   2. BCG and Polio Vaccines
   3. DPT and Rabbies Vaccine
   4. Shick's Test.

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   5×3=15

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