Download RTMNU B.Pharma 5th Semester 2015 Winter Pharmaceutical Medicinal Chemistry 1 Question Paper

NTK/KW/15/6994

Faculty of Pharmacy

B.Pharm. Fifth Semester (C.B.S.) Examination

--- Content provided by‌ FirstRanker.com ---

PHARMACEUTICAL MEDICINAL CHEMISTRY—?

Paper-II (5 T 2)

[Time-Three Hours]

[Full Marks-80

N.B. :— (1) Question No. 1 is compulsory.

--- Content provided by‌ FirstRanker.com ---

(2) Solve any FOUR questions from the remaining.

(3) Discuss the reaction, mechanism wherever necessary.

1. Solve any five of the following : 20
   1. Write a brief note on drug receptor interactions.
   2. What are bronchodilators ? Write chemical structures and names of any two compounds of this class.
   3. Write chemical name, structure and synthesis of Lidocaine.

   --- Content provided by‌ FirstRanker.com ---

   4. Discuss SAR of antiepileptic drugs.
   5. Write in detail about Glucuronic acid conjugation reaction of drug metabolism.
   6. Enlist various physicochemical factors affecting biological activity of drugs.
   7. Write in brief about treatment of Urinary tract infections.

--- Content provided by‌ FirstRanker.com ---

2. 1. What are structurally non specific drugs? Classify general anesthetics. 7
   2. Write chemical classification of local anesthetics.
3. 1. Write classification, SAR and uses of barbiturates. 7
   2. Write chemical name, structure, structure activity relationship, mechanism of action, synthesis, uses and metabolism of benzodiazepine class of drugs. 8

   --- Content provided by​ FirstRanker.com ---

4. Write a detailed note on opioids as analgesics. 15
5. 1. Give classification of oral hypoglycemics. 7
   2. Explain applications of prodrugs with the help of suitable examples. 8

--- Content provided by‌ FirstRanker.com ---

6. 1. Summarize mechanism of action and SAR of drugs used in the treatment of psychoses. 7
   2. Write classification of antidepressants giving Synthesis of any one drug of this class. 8
7. Write notes on any three of the following : 15
   1. Prostaglandins.
   2. Treatment of Parkinsonism.

   --- Content provided by FirstRanker.com ---

   3. NSAIDs as antiinflammatory agents.
   4. Treatment of Allergic Rhinitis.

More Question Papers at: FirstRanker.com

--- Content provided by⁠ FirstRanker.com ---