Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 5th Semester 2015 Winter Pharmaceutical Medicinal Chemistry 1 Question Paper
Faculty of Pharmacy
B.Pharm. Fifth Semester (C.B.S.) Examination
PHARMACEUTICAL MEDICINAL CHEMISTRY?I
Paper?II (5 T 2)
Time?Three Hours] [Full Marks?80
N.B. :? (1) Question N0. 1 is compulsory.
(2) Solve any FOUR questions from the remaining.
(3) Discuss the reaction, mechanism wherever
necessary.
1. Solve any five of the following : 20
(a) Write a brief note on drug receptor interactions.
(b) What are bronchodilators ? Write chemical structures
and names of any two compounds of this class.
(c) Write chemical name, structure and synthesis of
Lidocaine.
((1) Discuss SAR 0f antiepileptic drugs.
(e) Write in detail about Glucuronic acid conjugation
reaction of drug metabolism.
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(f)
(g)
(a)
(b)
(a)
(b)
Enlist various physicochemical factors affecting
biological activity of drugs.
Write in brief about treatment of Urinary tract
infections.
What are structurally non speci?c drugs ? Classify
general anesthetics. 7
Write chemical classi?cation of local anesthetics.
8
Write classi?cation, SAR and uses of barbiturates.
7
Write chemical name, structure, structure activity
relationship, mechanism of action, synthesis, uses
and metabolism of benzodiazepine class of drugs.
8
Write a detailed note on opioids as analgesics. 15
(a)
(b)
(a)
(b)
Give classi?cation of oral hypoglycemics. 7
Explain applications of prodrugs with the help of
suitable examples. 8
Summarize mechanism of action and SAR of drugs
used in the treatment of psychoses. 7
Write classi?cation of antidepressants giving Synthesis
of any one drug of this class. 8
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7. Write notes on any three of the following : 15
(a)
(b)
(C)
(d)
Prostaglandins.
Treatment of Parkinsonism.
NSAIDS as antiin?ammatory agents.
Treatment of Allergic Rhinitis.
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This post was last modified on 19 January 2020