Download RTMNU B.Pharma 5th Semester 2015 Winter Pharmaceutics V (Physical Pharmacy) Question Paper

NTK/KW/15/6993

Faculty of Pharmacy

B.Pharm. Fifth Semester (C.B.S.) Examination

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PHARMACEUTICS-V

(Physical Pharmacy)

Paper-I (5 T 1)

[Time-Three Hours]

[Full Marks-80

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N.B. :— (1) Question No. 1 is compulsory.

(2) Solve any FOUR questions from the remaining.

(3) Draw neat labeled diagram wherever necessary.

(4) Discuss the reaction, mechanism wherever necessary.

(5) Use of electronic calculator is permitted.

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(6) Assume suitable data wherever necessary.

1. Solve any five :
   1. Define colloids. Give types of colloids.
   2. What is spreading coefficient ? Derive equation for spreading coefficient.
   3. Disperse systems are thermodynamically unstable, justify.
   4. Define :
      1. Specific surface

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      2. Particle number
      3. Equivalent spherical diameter
      4. True density.
   5. Explain cloud point and kraft point.

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   6. Why are flocculated suspensions preferred over deflocculated ones ?
   7. How does change in temperature leads to destabilization of emulsion ?
2. Define critical micelle concentration. Explain phenomenon of micelle formation and explain various factors affecting micelle formation.
3. Describe various properties of colloids for determination of molecular weight of polymers.

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4. 1. Define adsorption Isotherm. Describe adsorption phenomenon of gases on solids with different adsorption Isotherm.
   2. Describe evaluation parameters for suspension.
5. 1. Define micromeritics. What is Edmundson equation ? How are the various statistical diameters calculated using Edmundson equation ?
   2. Describe Coulter counter method for determination of particle volume.

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6. 1. Describe mechanism of droplet stabilization.
   2. Explain various instability problems of emulsion.
7. Write short notes on (any two) :
   1. Micellar Solubilization

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   2. Controlled flocculation
   3. Assessment of shelf life of emulsion
   4. Derived properties of powder.

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