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Download RTMNU B.Pharma 5th Semester 2017 Summer Pharmaceutical Medicinal Chemistry 1 Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 5th Semester 2017 Summer Pharmaceutical Medicinal Chemistry 1 Question Paper

This post was last modified on 19 January 2020

This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University


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B.Pharm. Semester—V (C.B.S.) Examination

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PHARMACEUTICAL MEDICINAL CHEMISTRY-I

Paper-2

NKT/KS/17/6565

Time : Three Hours]

[Maximum Marks : 80

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Note :-(1) Question No. 1 is compulsory.

(2) Attempt any four questions from remaining.

(3) Draw neat labelled diagrams wherever necessary.

(4) Discuss the reaction, mechanism wherever necessary.

  1. Solve any five of the following : 5×4=20
    1. Draw diagram of blood brain barrier and discuss its role.
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    3. Draw structure and write chemical name, uses and synthesis
    4. Explain with structures metabolism of paracetamol and write about its actions and toxicity.
    5. What is prodrug ? Discuss principles of prodrug designing with examples.
    6. Discuss oxytocics with examples.
    7. Draw structure and write IUPAC name, uses and synthesis of Xylocaine.
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    9. Write note on expectorants and antitussives.
  2. Explain metabolism of histamine. Write in detail about chemical classification, mode of action and side effects of H₁ and H₂ antihistaminic agents. 15
  3. Define convulsions. Classify chemically anti-convulsant agents. Write mode of action and synthesis of one drug from hydontoin class. 15
    1. Define and classify anti-depressants. 8
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    3. Write note on thyroid hormones and antithyroid drugs. 7
  4. What are NSAIDs ? Discuss salol principle and write in detail about chemical classification, mode of action and side effects of NSAIDs. 15
    1. Describe phase II metabolism reactions with examples. 7
    2. Write note on anti-asthmatic agents. 8
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  5. Write notes on any three of the following : 5×3=15
    1. Physicochemical parameters affecting drug action.
    2. Prostaglandins and eicosanoids.
    3. CNS stimulant agents.
    4. Drugs used in Parkinsonism.
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    6. Sedatives and hypnotics.

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This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University

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