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B.Pharm. Semester—V (C.B.S.) Examination
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PHARMACEUTICAL MEDICINAL CHEMISTRY-I
Paper-2
NKT/KS/17/6565
Time : Three Hours]
[Maximum Marks : 80
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Note :-(1) Question No. 1 is compulsory.
(2) Attempt any four questions from remaining.
(3) Draw neat labelled diagrams wherever necessary.
(4) Discuss the reaction, mechanism wherever necessary.
- Solve any five of the following : 5×4=20
- Draw diagram of blood brain barrier and discuss its role.
- Draw structure and write chemical name, uses and synthesis
- Explain with structures metabolism of paracetamol and write about its actions and toxicity.
- What is prodrug ? Discuss principles of prodrug designing with examples.
- Discuss oxytocics with examples.
- Draw structure and write IUPAC name, uses and synthesis of Xylocaine.
- Write note on expectorants and antitussives.
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- Explain metabolism of histamine. Write in detail about chemical classification, mode of action and side effects of H1 and H2 antihistaminic agents. 15
- Define convulsions. Classify chemically anti-convulsant agents. Write mode of action and synthesis of one drug from hydontoin class. 15
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- Define and classify anti-depressants. 8
- Write note on thyroid hormones and antithyroid drugs. 7
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- What are NSAIDs ? Discuss salol principle and write in detail about chemical classification, mode of action and side effects of NSAIDs. 15
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- Describe phase II metabolism reactions with examples. 7
- Write note on anti-asthmatic agents. 8
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- Write notes on any three of the following : 5×3=15
- Physicochemical parameters affecting drug action.
- Prostaglandins and eicosanoids.
- CNS stimulant agents.
- Drugs used in Parkinsonism.
- Sedatives and hypnotics.
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This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University
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