This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University
TKN/KS/16-7000
Sixth Semester Examination for the Degree of Bachelor of Pharmacy
PHARMACEUTICAL MEDICINAL CHEMISTRY - II
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Paper 6 T2
Time: Three Hours ] [Max. Marks: 80
N. B. : (1) Question no. 1 is compulsory.
(2) Solve any four questions from the remaining.
(3) Draw neat labeled diagram wherever necessary.
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(4) Discuss the reaction, mechanism wherever necessary.
(5) Assume suitable data wherever necessary.
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Solve any Five of the following :- 20
- Write in detail chemistry of tetracycline antibiotics.
- Describe malaria life cycle in detail.
- Write a brief note on antimetabolites.
- Write chemical name structure and synthesis of Iodoxuridine.
- Discuss SAR of chloramphenicol antibiotics.
- Write in brief about anthelmintics agents.
- Explain computer aided drug designing.
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Classify antibiotics with examples and structure and give uses of one drug from each class. Discuss stability of β-Lactum antibiotics in acidic condition and outline synthesis of Ampicillin. 15
TKN/KS/16-7000 Contd.
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- Give classification of antimalarial agent and discuss SAR of 4-amino quinoline derivatives. 8
- What is crystal urea ? How it is prevented ? Explain with examples. 7
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What are antineoplastic agent ? Give classification. MOA and uses of antineoplastic agents and outline synthesis of chlorambucil. 15
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- Give classification of antimycobacterial agent. Explain rationale of combinations used in therapy. Give any one synthesis from it. 8
- Classify antiviral drugs with examples. Discuss drugs use in AIDS. 7
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- What is Genetic Engineering ? Give its application in pharmaceutical formulations. 8
- Give detail account of molecular modeling in drug design. 7
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Write notes on any three of the following :- 15
- Antifungal Agent.
- Antiamoebic Agent.
- Types of QSAR.
- Antiseptic and Disinfectant.
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TKN/KS/16-7000 2
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This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University