Download RTMNU B.Pharma 6th Semester 2016 Winter Pharmacology 4 Question Paper

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B.Pharm. Semester–VI (C.B.S.) Examination

PHARMACOLOGY-IV

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Paper-3 (6T3)

[Full Marks: 80

N.B. :- (1) Question No. 1 is compulsory.

(2) Solve any FOUR questions from the remaining.

1. Solve any five of the following :
   1. Why probenicid is administered with penicillin ?

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   2. Write examples of antithyroid drugs and their therapeutic uses.
   3. Explain inclusion and exclusion criteria in clinical trials.
   4. Write mode of action and adverse effects of aminoglycoside antibiotics.
   5. Enlist first line and second line drugs used in treatment of tuberculosis.
   6. Write job responsibilities of CRO.

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   7. Write functions of :
      1. Parathyroid hormone
      2. Calcitonin.
2. (a) Describe in detail pharmacology of insulin.
   

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   (b) Classify various oral hypoglycemic agents and explain their mode of action.
3. (a) Classify ß-lactum antibacterial and write its mechanism of action.
   (b) Write spectrum, therapeutic used and adverse effects of various classes of penicillins.
4. Classify antineoplastic agents according to their mode of action. Explain in detail pharmacology of alkylating agents.
5. (a) Explain the cycle of malarial parasite. Write in brief about drugs acting on these different phases.
   

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   (b) Write note on systemic antifungal agents.
6. (a) Describe various designs of clinical trials with advantages and disadvantages.
   (b) Write in brief about Immunosuppressants.
7. Write short notes on any two :
   1. Glucocorticoids
   2. Anti-viral drugs

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   3. ICH guidelines for clinical trials.

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