This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University
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B.Pharm. Sixth Semester (C.B.S.) Examination
PHARMACEUTICAL MEDICINAL CHEMISTRY-II
Paper-2
NKT/KS/17/6571
[Maximum Marks: 80
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N.B. :— (1) Question No. 1 is compulsory.
(2) Solve any four questions from remaining.
(3) Draw neat labelled diagram wherever necessary.
(4) Assume suitable data wherever necessary.
(5) Discuss the reaction, mechanism wherever necessary.
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- Solve any five of the following : 5×4=20
- Write chemical name, use, side effect and synthesis of Isoniazid.
- Discuss in brief about macrolide antibiotics.
- Differentiate between malignant and benign tumor. Explain different terminologies used to denote cancer.
- Explain 8 amino quinoline derivatives as antimalarials.
- Explain in brief about antiamoebic agents.
- Write chemical name, use and synthesis of chloroquine phosphate.
- Discuss mode of action of sulphonamide.
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- (a) Write in detail SAR of aminoglycoside antibiotics. 8 (b) Explain concept of genetic engineering and write application of it in medicinal chemistry. 7
- What is neoplasm ? Classify chemically anti-cancer agents and discuss about their mode of action and toxicity. Give synthesis of any one agent from it. 15
- (a) Explain different physicochemical Properties and common approaches used in drug designing. 8 (b) Discuss stereochemistry of penicillin and write detail account on its analogues. 7
- Draw structure of virus. Write four examples of each DNA and RNA type of viruses. Classify antiviral agents chemically and write a note on drugs used in treatment of AIDS. 15
- (a) What is DOT therapy ? Write in detail about mode of action, toxicity and chemical classification of antileprotic agents. 7 (b) Write chemical classification and mode of action of antifungal agents. 8
- Write notes on any three of the following : 5×3=15
- SAR of tetracycline antibiotics
- Combinatorial chemistry
- Lactamase inhibitors
- Anthelmintic agents.
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NXO-20314
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This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University
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