Download RTMNU B.Pharma 6th Semester 2017 Summer Pharmacology 4 Question Paper

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B.Pharm. Sixth Semester (C.B.S.) Examination

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PHARMACOLOGY-IV

NKT/KS/17/6572                                                                                                                                   [Maximum Marks : 80

Paper-3                                                                                                                                                 Time: Three Hours]

N.B. :— (1) Question No. 1 is compulsory.

          (2) Solve any four questions from remaining.

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          (3) Draw neat labelled diagram wherever necessary.

          (4) Assume suitable data wherever necessary.

          (5) Discuss the reaction, mechanism wherever necessary.

          (6) Use of electronic calculator is permitted.

1. Give the pharmacology of the following drugs (any five) :                                                                                                                                                         5×4=20
   1. Acyclovir

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   2. Cotrimoxazole
   3. Metronidazole
   4. Ketoconazole
   5. Propylthiouracil
   6. Cephalosporin

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   7. Metformin.
2. 1. What is microdosing ? Discuss all phases of clinical trials.                                                                                                                                        10
   2. Explain informed consent form. Justify the the relationship of informed consent form with clinical trial.                                                                                                                                                                      5

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3. Explain in detail malarial cycle. Classify anti-malarial drugs according to their inhibition at various stages of malarial cycle with detail pharmacology.                                                                                                                                           15
4. What is diabetes mellitus ? Explain in detail the treatment strategy for various types of diabetes mellitus.                                                                                                                                                                     15
5. 1. What are various causes and mechanism of cancer development ? What are recent developments in anticancer drug therapy ?                                                                                                                                                                     10
   2. How toxicities of anti-cancer drugs can be controlled ?                                                                                                                                                     5

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6. 1. Describe the fate and metabolic effect of thyroid hormones.                                                                                                                                                  7
   2. Write in detail about immunomodulators.                                                                                                                                                      8
7. Write short notes on (any three) :                                                                                                                                                         3×5=15
   1. Fluroquinolones
   2. Antitubercular drugs

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   3. Corticosteroid
   4. Adverse events in clinical trial
   5. Human immunodeficiency virus.

NXO-20315

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