Download RTMNU B.Pharma 3rd Semester 2015 Winter Pharmaceutical Chemistry 3 (Organic) Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 3rd Semester 2015 Winter Pharmaceutical Chemistry 3 (Organic) Question Paper

NTK/KW/ 1 5/ 6982
Faculty of Pharmacy
B.Pharm. Third Semester (C.B.S.) Examination
PHARMACEUTICAL CHEMISTRY?III (ORGANIC)
Paper?II (3T-2)
Time : Three Hours] [Full Marks : 80
NB. :? (1) Question N0. 1 is compulsory.
(2) Solve any FOUR questions from the remaining.
(3) Draw neat labeled diagram wherever necessary.
1. Solve any FIVE 0f the following : 5X4=20
(a) Write the mechanism of Ho?nann degradation reaction.
(b) Justify that SN 1 reactions are accompanied by
rearragement.
(c) Explain conformation of n?butane.
((1) Why cyclopropane always undergo ring opening
reaction ?
(e) State how heat of hydrogenation proves unusual
stability of benzene.
MVM?46559 1 (Contdl)

(1) Explain any two reactions of carboxylic acid. 7. Discuss the electrophilic aromatic substitution reaction of
(g) Aldehydes are more reactive than ketone. Explain. benzene Wlth I
_ _ _ . (a) Nitration
2. (a) Dlscuss Aldol condensatlon w1th sultable examples.
8 (b) Sulphonation
(b) Explain Cannizzano?s reactions with suitable examples. (C) Frledel-Cra? S alkylatlon
7 (d) F riedel-Craft?s acylation
3. Give detailed account of SN2 reaction including mechanism, (e) Halogenation. 15
orientation and reactivity. 15
4. Outline the laboratory synthesis of following from
benzene :
(a) p?chloro benzoic acid
(b) p?toluidine
(c) Diphenyl methane
(d) m-bromo phenol
(e) Styrene. 15
5. Write in detail about method of preparation of alkenes
using suitable examples. 15
6. (a) Elaborate the detailed account of E2 mechanism
supporting evidences and sterochemistry. 8
(b) Write a short note on Hinsberg test. 7
MVM?46559 2 (C0ntd.) MVM?46559 3 1250