Download RTMNU B.Pharma 4th Semester 2015 Winter Pharmaceutical Microbiology and Immunology 2 Question Paper

NTK/KW/15 – 6991

Fourth Semester Examination for the Degree of Bachelor of Pharmacy

PHARMACEUTICAL MICROBIOLOGY AND IMMUNOLOGY–II

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Paper - 4 T 5

Time: Three Hours ] [Max. Marks : 80

N. B. : (1) Question No. 1 is Compulsory.

(2) Solve any four questions from the remaining.

(3) Draw neat labeled diagram wherever neces- sary.

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1. Solve any five questions :—
   1. Explain the term D value and Z value.
   2. What are antigens ? Explain in short.
   3. Differentiate between exotoxins and endotoxins.
   4. Comment on sources of contamination in aseptic area.
   5. Give the applications of gaseous sterilization and radiation sterilization.

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   6. Differentiate between vaccines and sera.
   7. Write the applications of antigen antibody reactions in medical and general microbiology. 5x4=20
2. 1. Classify the methods of sterilization. Explain the filteration as method of sterilization. 8 NTK/KW/15-6991 Contd.
   2. Discuss in short sterilization indicators. 7

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3. 1. Describe the method of preparation of diphtheria antitoxin. 8
   2. Write a note on tuberculin as diagnostic agent. 7
4. Describe the non-specific defense mechanism of host. 15

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5. Explain antigen-antibody reactions. 15
6. What are hypersensitivity reactions ? Describe the different types of hypersensitivity reactions. 15
7. Write short note on (any three) :—
   1. Types of Immunity.
   2. Laminar air flow unit.
   3. Phenol coefficient test.

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   4. ELISA. 5x3=15

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