Download RTMNU B.Pharma 4th Semester 2016 Summer Pharmacology 2 Question Paper

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1. Solve any FIVE (Justify the Statements) : (4×5=20)
   1. Digitalis is called cardiotonic

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   2. Vitamin B2 is used as haematinic.
   3. Vasodilators and Vasoconstrictors are ideal in shock therapy.
   4. Spironolactone is potassium sparing diuretic.
   5. Quinidine is antiarrhythmic drug.
   6. HMG-COA reductase inhibitors are hypolipidaemic agents.

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   7. Angiotensin converting enzyme inhibitors are mixed veno-and arteriodilators.
2. 1. What are the various nonsteroidal anti-inflammatory agents ? Discuss the mechanism of action, indications of any one drug belonging to this class. (10)
   2. Give the steps involved in prostaglandin synthesis. (5)

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3. 1. Write therapeutic potential of statins. (7)
   2. Describe the compensatory mechanisms operated in congestive heart failure. (8)
4. 1. Explain the synthesis, storage and distribution of histamine. (7)
   2. Discuss the mechanisms involved in arrhythmias. Classify antiarrhythmics. (8)

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5. 1. Give the classification of anticoagulants with examples, mode of action and adverse effects. (10)
   2. Write a note on loop diuretics. (5)
6. 1. Describe the pathophysiology of angina pectoris and suggest the treatment for it. (7)

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   2. Explain the therapeutic potential of ß-Blockers. (8)
7. Write short notes on any THREE : (15)
   1. 5-hydroxytryptamine and its antagonists.
   2. Haematinics
   3. Pharmacology of Fibrinolytics

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   4. Anti-diuretic Hormone.

N.B. :— (1) Question No. 1 is compulsory.

(2) Solve any FOUR questions from the remaining.

(3) Draw neat labeled diagram wherever necessary.

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