Download OU M.Pharma Pharmaceutics 1st Sem 2018 1154PCI Drug Delivery Systems Question Paper

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Code No. 1154/PCI

FACULTY OF PHARMACY

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M. Pharmacy (Pharmaceutics) I-Semester (PCI) (Main) Examination, February 2018

Subject: Drug Delivery Systems

Time: 3 Hrs Max. Marks: 75

Note: Answer any five questions. All questions carry equal marks.

1. a) Discuss in detail about biodegradable and natural polymers. (8)
   

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   b) Write a note on customized drug delivery system. (7)
2. Classify various types of rate preprogrammed drug delivery systems with suitable examples. (15)
3. Give detailed account of various formulation mechanisms in gastric retentive drug delivery system. (15)
4. a) Discuss in detail formulation approaches for TDDS with suitable examples. (10)
   b) What are barriers of permeation for TDDS? (5)

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5. a) Discuss about different approaches to overcome ocular barrier. (8)
   b) Explain uptake of antigen in vaccine delivery system with neat diagram. (7)
6. Write about various formulation approaches and evaluation of protein and peptide delivery systems. (15)
7. a) Explain principle involved in mucoadhesion. Describe various theories to explain mucoadhesion. (8)
   b) Explain in brief mechanism of drug release from sustained release formulation. (7)

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8. Write a short note on
   1. Bioresponsive drug delivery systems. (8)
   2. pH activated drug delivery system. (7)