Download OU (Osmania University) M.Pharma-Pharmacology (Master of Pharmacy) 1st Sem 2020 6118PCI Pharmacological And Toxicological Screening Methods I Previous Question Paper
Code No. 6118/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmacology) I-Semester (PCI) (Main & Backlog) Examination,
January 2020
Subject: Pharmacological and Toxicological Screening Methods - I
Time: 3 Hrs Max. Marks: 75
Note: Answer Any Five Questions. All Questions Carry Equal Marks.
1 (a) Describe in detail abt regulations for laboratory animal care as per CPCSEA
Guidelines. 10
(b) Enlist the applications of transgenic animals in preclinical research. 5
2 Define memory. List t the animal models for evaluating the test drug for improving
memory and describe any three models. 15
3 Describe the preclinical screening procedures for the following:
(a) Antifertility agents 8
(b) Analgesics 7
4 Define diabetes. List t the methods available to induce diabetes and describe
three models in the screening of anti-diabetic agents. 15
5 Explain the in vitro and in vivo screening methods for immunomodulators. 15
6 Write short notes on:
(a) Alternate animal experiments 7
(b) Immunoassay for digoxin 8
7 Describe the screening methods for the evaluation of the following activities of a
compnd
(a) Hepatoprotective drugs 8
(b) Anti ulcer agents 7
8 Describe the screening methods used to evaluate the therapeutic activity of the
following:
(a) Anti-asthmatics 8
(b) Diuretics 7
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This post was last modified on 19 July 2020