Download OU M.Pharma Ph.Analysis 2nd Sem 2018 1206PCI Modern Bio Analytical Techniques Question Paper

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FACULTY OF PHARMACY

M. Pharmacy (Pharm. Analysis) II-Semester (PCI) (Main) Examination, August 2018

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Subject: Modern Bio Analytical Techniques

Time: 3 Hrs Max. Marks: 75

Note: Answer any five questions. All questions carry equal marks.

1. Write notes on bio analytical method validation as per FDA Guidelines? (15)
2. Explain the factors effecting for enhancement of bioavailability of drugs? (15)

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3. Describe the Cytochrome P450-based drug interactions ? (15)
4. Write brief notes on
   1. Various types of cell culture (8)
   2. LC-MS in bioactivity screening and proteomics (7)
5. Describe the principles and applications of cell viability assays of MTT assays?(15)

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6. Write the alternate methods for dissolution testing? (15)
7. 1. Define and explain bioavailability, bioequivalence and biosimilar. (6)
   2. Write about various designs to conduct bioavailability studies. (9)
8. 1. Discuss about the bioanalytical methods such as protein precipitation. (7)

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   2. Describe the various solubility techniques; (8)

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