Download OU M.Pharma Ph.Analysis 2nd Sem 2020 6135PCI Modern Bio Analytical Techniques Question Paper

FirstRanker.com

Code No: 6135/PCI

FACULTY OF PHARMACY

--- Content provided by‍ FirstRanker.com ---

M. Pharmacy (Pharma Analysis) II- Semester (PCI) (Suppl.) Examination, January 2020

Subject: Modern Bio Analytical Techniques

Time: 3 Hrs Max Marks: 75

Note: Answer Any Five Questions. ALL Questions carry Equal Marks.

1. a) What is the importance of extraction of drugs and metabolites from biological matrices? (5)

   --- Content provided by‌ FirstRanker.com ---

   b) Describe the bioanalytical method procedure for liquid and solid phase extraction? (10)

2. a) Mention the different alternative methods of dissolution testing. (4)

   b) Define solubility & permeability based on biopharmaceutics classification system. (11)

--- Content provided by‍ FirstRanker.com ---

3. Describe various drug (PK-PD) interactions? (15)

4. Discuss the principles and applications of flow cytometry. (15)

5. Write the different methods for the assessment of bioavailability and bioequivalence? (15)

   --- Content provided by‌ FirstRanker.com ---

6. a) Explain the drug permeability by in-vivo method? (7)

   b) Write notes on cross over design. (8)

7. Write notes on the following:

   --- Content provided by FirstRanker.com ---

   a) Drug interaction linked to transporters (7)

   b) Cryopreservation techniques. (8)

8. Discuss about the design and evaluation of bioequivalence studies. (15)

--- Content provided by⁠ FirstRanker.com ---

FirstRanker.com