Download OU M.Pharma Ph.Chemistry 2nd Sem 2018 1222PCI Advanced Organic Chemistry Ii Question Paper

Download OU (Osmania University) M.Pharma-Ph.Chemistry (Master of Pharmacy) 2nd Semester 2018 1222PCI Advanced Organic Chemistry Ii Previous Question Paper

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Code No. 1222/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharm. Chemistry) II-Semester (PCI) (Main) Examination,
August 2018
Subject : Advanced Organic Chemistry-II
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 a) Discuss the basic Principles of green chemistry
b) Discuss the merits, demerits and any five applications of micro wave assisted
reactions. (8+7)
2 What are pericyclic reactions? Discuss Cycloaddition and electrocyclic reactions
in presence of heat and photo light with mechanism and stereochemistry.
3. a) What is homogens and heterogons catalysis? Explain advantages and
disadvantages. Discuss examples of drug syntheses involving Wilkinson catalyst
and Ziegler ? Natra catalyst (one each)
b) Discuss the theory and applications of phase transfer catalysts (8+7)
4. Discuss different methods of asymmetric synthesis with suitable examples
5 Explain the basic principles of solid phase peptide synthesis. Write abt solid
supports, linkers, protecting and de protecting grps used in solid phase peptide
synthesis
6. a) Discuss any five synthetic applications of Ultra snd assisted reactions
b) Discuss sequential strategies in solution phase peptide synthesis with two case
studies (5+10)
7. a) Explain Cahn, Ingold, Prelog (CIP) sequence rules with suitable examples
b) Discuss cis-trans isomerism in cyclic and dble bond containing compo unds (7+8)
8. Write a note on: (5+5+5)
a) Photo-oxidation reactions
b) Sigmatropic reactions
c) Bio catalysts
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