Download OU M.Pharma Ph.Chemistry 2nd Sem 2018 1224PCI Pharmaceutical Process Chemistry Question Paper

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FACULTY OF PHARMACY

M. Pharmacy (Pharmaceutical Chemistry) II-Semester (PCI) (Main) Examination, August 2018

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Subject: Pharmaceutical Process Chemistry

Time: 3 Hrs Max. Marks: 75

Note: Answer any five questions. All questions carry equal marks.

1. a) Discuss the synthetic strategies in Scale up Process b) Write the validation of Large scale Process (7+8)
2. a) Explain the Theory of filtration and its limitations b) Discuss the factors affecting Crystallization (9+6)

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3. a) Write the kinetics and Mechanism of aromatic nitration. b) Discuss the different oxidizing agents used in oxidation
4. a) Discuss the production of penicillin by Fermentation b) Write a note on streamlining reaction steps and rte of selection in reaction progress kinetic analysis. (7+8)
5. a) Write a detail note on OHSAS - 18000 b) Write abt fire hazards and types of fire and fire extinguishers (8+7)
6. a) Give a note on Impurities in API (Sources, Types including genotoxic impurities) (7+8) b) Write abt Effluent Management system in Industries.
7. a) Discuss abt the types of evaporators used in evaporation b) Write the Case study on Industrial Halogenation (8+7)

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8. a) Write the Importance of ISO-14001 in Industrial Safety b) Explain abt azeotropic distillation (9+6)