Download OU M.Pharma Pharmaceutics 2nd Sem 2018 1209PC Molecular Pharmaceutics Nano Technology And Targeted Drug Delivery Systems Question Paper

Download OU (Osmania University) M.Pharma-Pharmaceutics (Master of Pharmacy) 2nd Semester 2018 1209PC Molecular Pharmaceutics Nano Technology And Targeted Drug Delivery Systems Previous Question Paper

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Code No. 1209/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutics) II-Semester (PCI) (Main) Examination, August 2018
Subject: Molecular Pharmaceutics
(Nano Technology and Targeted Drug Delivery Systems)
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 a) Explain the concepts, events and biological processes involved in drug
targeting. (8)
b) Explain in detail abt targeting of drugs to tumor cells. (7)
2. Explain the methods of preparation and evaluation of nanoparticles. (15)
3 a) Explain the methods of preparation and evaluation of microspheres. (10)
b) Explain the methods of preparation of aquasomes. (5)
4 a) Write abt containers, propellants and evaluation tests for pharmaceutical
aerosols. (10)
b) Explain abt intranasal drug delivery system. (5)
5 a) Explain abt bone marrow transplantation in exvivo gene therapy. (10)
b) Give a brief note on invivo gene therapy (5)
6 a) Discuss in detail gene expression systems (both viral and nonviral gene
transfer). (10)
b) Give an accnt of liposomal gene delivery system. (5)
7. Give a brief accnt of i) aptamers; ii) Therapeutic antisense molecules. (8+7)
8. Explain the methods of preparation and evaluation of liposomes. (15)
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