Download OU M.Pharma Pharmaceutics 2nd Sem 2019 13163PCI Molecular Pharmaceutics Nano Technology And Targeted Drug Delivery Systems Question Paper

Download OU (Osmania University) M.Pharma-Pharmaceutics (Master of Pharmacy) 2nd Semester 2019 13163PCI Molecular Pharmaceutics Nano Technology And Targeted Drug Delivery Systems Previous Question Paper

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Code No. 13163/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutics) II-Semester (PCI) (Suppl.) Examination, February 2019
Subject: Molecular Pharmaceutics
(Nano Technology and Targeted Drug Delivery Systems)
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1. a. What are the ideal properties of a carrier? (5)
b. Explain different types of drug targeting with examples? (10)
2. a. What are the limitations of drug targeting to tumr? Explain EPR targetin g? (7)
b. What are the active targeting methods to target tumr? (8)
3. a. Explain blood brain barrier? What the factors affecting drug transport across
the BBB? (6)
b. Explain varis non -invasive targeting methods to brain? (9)
4. a. Describe in detail varis methods of preparation of microspheres? (10)
b. Explain the drug release mechanism from microspheres? (5)
5. a. Explain in detail nasal drug delivery system? (10)
b. Write a note on preparation of Monoclonal antibodies? (5)
6. a. What are aerosols? Explain varis propellants used in the manufacturing of
Aerosols. (7)
b. Explain different methods to characterize aerosols? (8)
7. a. Define gene therapy? Explain few diseases targeted for treatment using gene
drug delivery system. (9)
b. Explain aptamers role in targeted cancer therapy? (6)
8. Write a note on following
a. Stealth liposomes
b. Phytosomes
c. Aquasomes (15)
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