Download OU M.Pharma Pharmacology 2nd Sem 2018 1214 Pharmacological And Toxicological Screening Methods Ii Question Paper

Download OU (Osmania University) M.Pharma-Pharmacology (Master of Pharmacy) 2nd Semester 2018 1214 Pharmacological And Toxicological Screening Methods Ii Previous Question Paper

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CODE:1214/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmacology) II?Semester (PCI) Main Examination,
August 2018
Subject : Pharmacological and Toxicological Screening Methods-II
Time : 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1. Write in detail on OECD guidelines for conducting toxicity studies. 15
2. (a) Describe in detail the flow chart of Preclinical studies. 10
(b) Explain the dermal toxicity studies. 5
3. Write abt the importance & Application of toxico kinetic?s. 15 (8)
4. (a) Write in detail abt safety pharmacology. 8
(b) Discuss in brief tier ?I safety pharmacology studies 7
5. Discuss in detail the importance of ICH guidelines for toxicity studies. 15
6. Write a note on
(a) The principles of regulatory toxicology. 7
(b) Alternative to animal models in preclinical toxicology studies. 8
7. (a) Write abt the risk assessment in male reproductive toxicity. 8
(b) Explain the single dose and repeat dose toxicity studies as per OECD
guidelines 7
8. (a) Discuss in detail abt IND studies 8
(b) Write a note on determination of LD
50
as per OECD- 423 guidelines 7
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