GTU BE/B.Tech 2019 Winter Question Papers || Gujarat Technological University
BE - SEMESTER- IV (New) EXAMINATION - WINTER 2019
Subject Name: Molecular Biology and Genetics
Time: 10:30 AM TO 01:00 PM
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Subject Code: 2140401
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GUJARAT TECHNOLOGICAL UNIVERSITYBE - SEMESTER- IV (New) EXAMINATION - WINTER 2019
Subject Name: Molecular Biology and Genetics
Time: 10:30 AM TO 01:00 PM
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Instructions:
- Attempt all questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
| Q.1 | (a) Why is genetic code triplet? | 03 |
| (b) Explain phenomenon of dominance. | 04 | |
| (c) What is the principle of independent assortment and how is this principle demonstrated in the results of a Two-gene (dihybrid) cross? | 07 | |
| Q.2 | (a) What is linkage? Explain its significance. | 03 |
| (b) What three types of RNA participate in protein synthesis And what is the role of each type of RNA? | 04 | |
| (c) Explain abnormality due to triosomy in autosomal chromosome. | 07 | |
| OR | ||
| (c) What is difference between dominance and epistasis? Explain any one epistasis with example. | 07 | |
| Q.3 | (a) Explain role of DNA polymerase and RNA polymerase in replication. | 03 |
| (b) Draw neat diagram of structure of tRNA. | 04 | |
| (c) Explain rho dependent and rho independent termination process. | 07 | |
| OR | ||
| (c) What is role of PCNA, RFC and RPA in eukaryotic replication? | 07 | |
| Q.4 | (a) What is post translational modification? Explain any two modifications in detail. | 03 |
| (b) Explain the process of formation of transcription bubble with diagram. | 04 | |
| (c) Explain the terms sense'strand, antisense strand and promoter. | 07 | |
| Q.5 | (a) Explain the process of synapsis in crossing over. | 03 |
| (b) What progeny is expected when a carrier female for haemophilia marries a normal male? Explain X linked recessive inheritance using above example. | 04 | |
| (c) | 07 | |
| OR | ||
| (c) What is role of primer in replication process? | 07 | |
| Q.5 | (a) Write a note on pleiotropy. | 03 |
| (b) When a colour blind man marries with a normal visioned female, what type of progeny is expected in F2 generation? | 04 | |
| (c) What is P site, A site and E site on ribosome? | 07 | |
| Q.5 | (a) What is primosome and replisome? | 03 |
| (b) Explain formation of initiation complex in prokaryotic translation. | 04 | |
| (c) | 07 | |
| OR | ||
| (c) Give properties of genetic code. | 07 | |
| Q.5 | (a) What is genetic material? What are its properties? | 03 |
| (b) Explain deletion, inversion and translocation mechanisms of chromosomal disorders. | 04 | |
| (c) | 07 | |
Date: 16/12/2019
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Total Marks: 70--- Content provided by FirstRanker.com ---
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