Subject Code: 2173606
GUJARAT TECHNOLOGICAL UNIVERSITY
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BE - SEMESTER- VII (New) EXAMINATION — WINTER 2019
Date: 26/11/2019
Subject Name: Medicinal Chemistry-II & Technology of Sterile Products
Time: 10:30 AM TO 01:00 PM
Instructions:
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- Attempt all questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 | (a) Define Ophthalmic dosage forms. What are the types of ophthalmic preparations? What are the general safety considerations in these preparations | 03 |
(b) Write short notes on Vitamin B7 & Vitamin E | 04 | |
(c) Define parenteral dosage forms. Describe the evaluation of Parenteral dosage forms. | 07 | |
Q.2 | (a) What are Eicosanoids? Give examples and what are their functions? | 03 |
(b) What are Pheromones? What are the different kinds of Pheromones?. Give suitable examples. What are the advantages of pheromones over insecticide | 04 | |
(c) Explain Vitamin K cycle and write its uses | 07 | |
OR | ||
(a) Write the synthesis of Riboflavin. | 03 | |
(b) Write a note on ocular delivery system | 04 | |
(c) Write a detailed note on surgical sutures & ligatures | 07 | |
Q.3 | (a) Write the synthesis of Haemin | 03 |
OR | ||
(b) What are the preformulation factors for Parenterals. | 04 | |
(c) Write a note on Blood products-and their preservation | 07 | |
Q.4 | (a) Illustrate the synthesis of Dipyrrylmethene intermediate of Chlrophyll- A | 03 |
(b) Explain the synthesis of collagen & uses of it. | 04 | |
(c) Write the synthesis of Vitamin A & vision cycle. | 07 | |
Q.5 | (a) Define pharmaceutical product stability and write a note on stability | 03 |
OR | ||
(b) Write the commercial synthesis of Thiamine & give its Biochemistry & uses. | 04 | |
(c) Explain Provitamin A, and uses & deficiency syndrome. | 07 | |
Q4 | (a) Discuss about Parenteral formulation components in detail | 03 |
(b) Differentiate between water soluble & fat soluble vitamins. | 04 | |
(c) Discuss about Protein & Peptide drugs, their route of administration & biomedical applications | 07 | |
Q.5 | (a) Write Vitamin C synthesis, discuss its sources, deficiency & uses. | 03 |
OR | ||
(b) Explain Vitamin B12 with its Biochemistry & kinetics. | 04 | |
(c) What are the functions of Carbohydrates and explain monosacchrides & Oligosacchrides. | 07 | |
(a) Write Vitamin B9 synthesis, discuss its sources, deficiency & uses. | 03 |
Total Marks: 70
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