GTU BE 2019 Summer Question Papers || Gujarat Technological University
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BE - SEMESTER-IV(NEW) — EXAMINATION - SUMMER 2019
Subject Code:2140401 Date:25/05/2019
Subject Name: Molecular Biology and Genetics
Time:02:30 PM TO 05:00 PM Total Marks: 70
Instructions:
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- Attempt all questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
| MARKS | |
|---|---|
| Q.1 (a) What is the role of primer in the process of replication? | 3 |
| (b) Explain genetic linkage. | 4 |
| (c) Write a note on semi conservative mode of replication. | 7 |
| Q.2 (a) What do you mean by gene? | 3 |
| (b) What is monocistronic and polycistronic mRNA? | 4 |
| (c) How was it proved that DNA is genetic material in prokaryotes? Explain | 7 |
| OR | |
| (c) Explain Mendel’s law of segregation with a suitable illustration. | 7 |
| Q.3 (a) What are promotors? | 3 |
| (b) Compare epistasis and dominance. | 4 |
| (c) Give the detailed account of enzymes used in replication. | 7 |
| OR | |
| Q.3 (a) Enlist different proteins participating in DNA replication initiation. | 3 |
| (b) Write a short note on pleiotropy. | 4 |
| (c) Explain in detail about epistasis. | 7 |
| Q.4 (a) What is the role of t-RNA and draw its general structure. | 3 |
| (b) What is the reason for amazing accuracy of replication? Explain. | 4 |
| (c) Explain post transcriptional processing of tRNA | 7 |
| OR | |
| Q.4 (a) What is the role of promoter in transcription? | 3 |
| (b) Write a short note on RNA polymerase. | 4 |
| (c) Discuss about post transcriptional modifications. | 7 |
| Q.5 (a) What are Okazaki fragments? | 3 |
| (b) Explain and represent schematically the “formation of initiation complex in bacteria” during protein synthesis. | 4 |
| (c) Give the overview of five stages of protein synthesis. | 7 |
| OR | |
| Q.5 (a) What do you mean by redundancy of genetic code? | 3 |
| (b) Explain the wobble hypothesis? | 4 |
| (c) Write a detailed note about post translational modification. | 7 |
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