GUJARAT TECHNOLOGICAL UNIVERSITY
BE - SEMESTER-V (NEW) EXAMINATION - SUMMER 2019
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Subject Code: 2150402 Date: 20/06/2019
Subject Name: Immunology
Time: 02:30 PM TO 05:00 PM Total Marks: 70
Instructions:
- Attempt all questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
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Q.1 (a) Mention the classes of antibodies with their heavy chains. 03
(b) Differentiate between Tc and Ty cells. 04
(c) Draw basic structure of immunoglobulin molecule with proper annotation. 07
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Q.2 (a) List major events of inflammatory response. 03
(b) Explain the terms adjuvant and hapten. 04
(c) Explain the process of positive and negative selection of T cells. 07
OR
(c) Explain the process of maturation of B cells. 07
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Q.3 (a) Enlist primary lymphoid organs. Explain its role in immune response. 03
(b) List four nonspecific components of innate immune system 04
(c) How is lectin pathway initiated? Explain formation of Membrane attack complex by above pathway. 07
OR
Q.3 (a) Draw structure of MHC class I and class II 03
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(b) Explain the basis of transplantation technology. 04
(c) Explain cause and remedies of type I Hypersensitivity. 07
Q.4 (a) What is MALT, GALT and CALT? 03
(b) Explain principle of western blotting. 04
(c) Write a short note on whole organism vaccine. 07
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OR
Q.4 (a) Name three factors that are unique to the alternative complement pathway 03
(b) What are cytokines? Give examples. 04
(c) Explain principle and working of ELISA. 07
Q.5 (a) What is advantage of vaccination? 03
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(b) Enlist different immune cells. Explain role of any two. 04
(c) Explain pathway for processing and presentation of endogenous antigens. 07
OR
Q.5 (a) What are toxoids and allergens? 03
(b) What is difference between primary and secondary immune response? 04
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(c) Explain hybridoma technology. 07
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