GUJARAT TECHNOLOGICAL UNIVERSITY
BE - SEMESTER-V (NEW) EXAMINATION - WINTER 2018
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Subject Code:2150305 Date:16/11/2018
Subject Name:Modelling & Simulation of Physiological systems
Time: 10:30 AM TO 01:00 PM Total Marks: 70
Instructions:
- Attempt all questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
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MARKS
Q.1 (a) Give an example of physiological system modelling. 03
(b) State difference between lumped parameter model and distributed parameter model. 04
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(c) Point out difference between engineering control system and physiological control system. 07
Q.2 (a) What is muscle stretch reflex? 03
(b) Explain generalized resistance property of mechanical, fluidic, thermal, and chemical system. 04
(c) Develop the mechanical equivalent of the electrical analog of respiratory mechanics shown in figure below. 07
OR
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(c) Explain linearized physiological model of skeletal muscle. 07
Q.3 (a) Explain determination of steady state operating point. 03
(b) Give static analysis of closed loop and open loop system. 04
(c) Draw & explain the curves of Cardiac Output and Venous Return for below given conditions. 07
a) Normal
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b) Moderate Exercise
c) Heart Failure
OR
Q.3 (a) Explain significance of time domain analysis of linear control systems. 03
(b) Explain transient response Descriptors. 04
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(c) What is starling’s law for regulation of cardiac output? Explain the model for change in cardiac output due to heart rate. 07
Q.4 (a) Describe the saccade characteristics. 03
(b) Explain the agonist & antagonist neurological signals. 04
(c) Draw & explain the steady-state analysis of glucose regulation for normal, Type- I & II diabetic patients. 07
OR
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Q.4 (a) Explain glucose-insulin regulation in body. 03
(b) Explain relationship between transient and frequency responses. 04
(c) Draw westheimer’s saccadic eye movement model. 07
Q.5 (a) What are the different types of eye movements executed by the occulomotor system? 03
(b) Name the “source” and “sink “operator of SIMULINK. 04
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(c) Describe the chemical regulation of ventilation with neat diagrams. 07
OR
Q.5 (a) How are frequency response of linear control system represented graphically? 03
(b) Explain regulation of heart rate and systemic blood pressure. 04
(c) Explain SIMULINK implementation of neuromuscular reflex model. 07
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