GUJARAT TECHNOLOGICAL UNIVERSITY
BE - SEMESTER-VII (NEW) EXAMINATION - WINTER 2018
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Subject Code: 2173606 Date: 19/11/2018Subject Name: Medicinal Chemistry-II & Technology of Sterile Products
Time: 10:30 AM TO 01:00 PM Total Marks: 70
Instructions:
- Attempt all questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
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MARKS
Q.1 (a) Define Parenteral dosage form. What are the special criteria for the 03 parenterals?
(b) Write a note on intraocular dosage forms. 04
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(c) Write the commercial synthesis of Vitamin B1 (Thiamine). Discuss 07 its deficiency and uses.
Q.2 (a) What are the advantages & disadvantages of Marine natural products. 03 Give one example each in anti-inflammatory & anti-fungal drugs.
(b) Write a note on packaging of ophthalmic products. 04
(c) Discuss about Parenteral formulation components in detail 07
OR
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(c) Discuss about the evaluation of parenteral preparations 07
Q.3 (a) Explain the method of Pyrogen testing 03
(b) Discuss the advantages of Pheromones over insecticides 04
(c) Write the steps in the biosynthesis of Eicosanoids. 07
OR
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Q.3 (a) Listout the comparison between Chlorophyll & Haemin 03
(b) List out the sections of a typical parenteral production area. Draw the 04 layout of parenteral preparation facility
(c) What are Pheromones? Discuss about its action & kinds of 07 Pheromones in detail.
Q.4 (a) Define Ophthalmic preparation. Discuss its safety factors. 03
(b) What are Pyrethroids?Give two examples. Discuss the uses of 04 pyrethroids.
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(c) Write any one synthesis of Pantothenic acid. Discuss its source, 07 deficiency & uses.
OR
Q.4 (a) Write the classifications of ocular drug delivery system 03
(b) Write the structure, use & MOA of any two Carbohydrate drugs. 04
(c) Write the synthesis of Vitamin C. Discuss its source, deficiency & 07 uses.
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Q.5 (a) What are Eicosanoids? What are its functions? 03
(b) Write the synthesis of Vitamin A2 from Vitamin A1 04
(c) Define pharmaceutical product stability and write a note on stability. 07
OR
Q.5 (a) Write a note on Chlorophyll, Chlorophyllin and uses. 03
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(b) Discuss about the Protein & Peptide drugs, their route of 04 administration & biomedical applications.
(c) Discuss the manufacturing considerations & techniques of 07 ophthalmic dosage forms.
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