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GUJARAT TECHNOLOGICAL UNIVERSITY
BE - SEMESTER-V (OLD) EXAMINATION - WINTER 2017
Subject Code:150304 Date: 30-11-2017
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Subject Name: Modelling & Simulation of Biological systems
Time: 10:30 am to 01:00 pm Total Marks: 70
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Instructions:
- Attempt all questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
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Q.1 (a) Give differences between engineering control system and physiological control system. 07
(b) Give difference between open loop and closed loop control system. Give two examples of each. 07
Q.2 (a) Draw and explain linear model of muscle mechanics, derive the equation of force for steady state isometric condition. (7
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(b) Develop the mechanical equivalent of the electrical analog of respiratory mechanics shown in below given figure. (7
OR
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(a) Draw and explain the linear model of respiratory mechanics. Derive the equation for Pao and Q. 07
Q.3 (a) Draw & explain time response and frequency response of glucose-insulin model for normal and type-2 diabetic patient. (07
(b) Describe cardiac output regulation with help of model and cardiac output curves 07
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OR
Q.3 (a) With neat figure describe linearized dynamic model of chemo reflex control of ventilation 07
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(b) Explain with neat diagram wetheimer’s saccade eye model. 07
Q.4 (a) Explain adaptive characteristics of muscle stretch reflex 07
(b) Explain superposition theorem and show how it is used to identify whether the system is linear or nonlinear. (07
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OR
Q.4 (a) Explain occulumotor eye muscle model with neat diagram. 07
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(b) Explain difference between time domain and frequency domain approach. 07
Q.5 (a) Explain distributed and local models. Derive the equation for steady state distribution of voltage along the nerve fiber. 07
(b) Draw simulink model of muscle stretch reflex. 07
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OR
Q.5 (a) With help of neat diagram explain cardiopulmonary model. 07
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(b) Explain with diagram that pupilliary light reflex is classic example of positive or negative feedback control systems. (07
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