Download RGUHS (Rajiv Gandhi University of Health Sciences) M Pharma (Master of Pharmacy) First Year (1st Year) May 2012 9223 Instrumental Methods Of Analysis Paper III Question Paper.
Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination ? May 2012
[Time: 3 Hours] [Max. Marks: 100]
INSTRUMENTAL METHODS OF ANALYSIS
PAPER III
(RS 2 & RS 3)
Q.P. CODE: 9223
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
1. Describe the validation of HPLC method. What is the importance of HPLC in pharmaceutical
sciences?
2. Discuss in detail the instrumentation and procedure involved in Fluorimetry. Which type of
compounds can be assayed by this method? Explain why it is sensitive and selective compare
to other methods.
3. Describe the different methods of particle size analysis in solid dosage forms. Explain the
importance of Particle size in various dosage forms.
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
4. Describe the principles and procedures involved in the various physicochemical methods of
Diuretics and Anti-tubercular drugs.
5. Give an account on the determination and significance of C, H and N in Organic compounds.
6. Discuss the principles and procedures involved in the determination of Anabolic steroids and
Alkaloids.
7. What is MBTH reagent? Which types of drugs can be determined by this reagent?
8. Write the principles and procedures involved in the determination of ?Hydroxyl group, aldehyde
and ketones. Give their uses in pharmaceutical analysis.
9. Explain the Determination of cloxacillin and ampicillin in multicomponent dosage forms.
SHORT NOTES 2 X 5 = 10 Marks
10. Write notes on Deyermination Barbiturates.
11. Write a note on analysis General anesthetic.
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This post was last modified on 20 December 2019