Download RGUHS M.Pharmacy First Year May 2016 9338 Biopharmaceutics And Pharmacokinetics Revised Scheme 4 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M Pharma (Master of Pharmacy) First Year (1st Year) May 2016 9338 Biopharmaceutics And Pharmacokinetics Revised Scheme 4 Question Paper.

Rajiv Gandhi University of Health Sciences, Karnataka
First Year M. Pharm Degree Examination ? May 2016

Time: Three Hours Max. Marks: 100 Marks

BIOPHARMACEUTICS AND PHARMACOKINETICS
(Revised Scheme 4)
Q.P. CODE: 9338

Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary

LONG ESSAYS (Answer any Two) 2 x 20 = 40 Marks
1.
Discuss the various factors affecting drug absorption.
2.
Derive an expression for calculating various pharmacokinetic parameters for a drug
administered as I.V infusion and follows one compartment kinetics.
3
Explain the determination of various pharmacokinetic parameters in multiple dosing with
respect to I.V and oral route.

SHORT ESSAYS (Answer any FIVE) 5 x 10 = 50 Marks
4.
discuss any two methods for the estimation of K
m

and V
max .

5.
Describe the various in vitro dissolution testing models.
6.
Explain the protocol for bioequivalence studies for drug formulations.
7.
Explain Phase I reactions in biotransformation of drugs.
8.
Explain the method of residual to determine the absorption rate constant. Mention its
limitations.
9.
Discuss MRT for various compartment models.

SHORT NOTES 2 x 5 = 10 Marks
10.
Plasma Proteins
11.
Concept of Clearance

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