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Rajiv Gandhi University of Health Sciences, Karnataka
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First Year M. Pharm Degree Examination – MAY 2016
Time: Three Hours
Max. Marks: 100 Marks
ADVANCES IN DRUG DELIVERY SYSTEMS
(Revised Scheme 4)
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Q.P. CODE: 9339
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two) 2 x 20 = 40 Marks
- Discuss in detail all the factors to be considered in the design of controlled release dosage forms.
- Explain the various approaches to controlled drug delivery system. Discuss the factors affecting mucoadhesion.
- Define and classify buccal drug delivery systems.
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SHORT ESSAYS (Answer any FIVE) 5 x 10 = 50 Marks
- What are permeation enhancers? Briefly explain the various techniques of permeation enhancement across the skin.
- Describe the evaluation of implantable drug delivery systems.
- Describe the principle involved in polymer precipitation methods of preparation of nanoparticles, explain any one technique in detail.
- Write a note on formulation and evaluation of solid lipid nanoparticles (SLN).
- Explain the concept of targeted drug delivery. Describe active drug targeting in detail.
- Discuss the formulation considerations of ocular drug delivery systems.
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SHORT NOTES 2 x 5 = 10 Marks
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- Write how transdermal drug delivery systems can be evaluated.
- Differentiate between oral conventional and oral controlled release dosage forms.
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