Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination – Nov 2011
[Time: 3 Hours] [Max. Marks: 100]
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INSTRUMENTAL METHODS OF ANALYSIS
PAPER III
(RS 2 & RS 3)
Q.P. CODE: 9223
Your answers should be specific to the questions asked.
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Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Discuss the instrumentation and procedure involved in Fluorimetry. Explain how it is more sensitive and selective compared to other spectrometric methods.
- Explain the principle and procedures involved in the quantitative determination of the following groups: (A) Hydroxyl (B) Esters.
- Elaborate on the quality control of radiopharmaceuticals with examples.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- How will you determine sodium and potassium by flame photometry?
- Discuss the assay of clotrimazole and tinidazole in multicomponent dosage forms.
- Explain the validation parameters of HPLC firstranker.component
- What is MBTH reagent? Which types of drugs can be determined by this reagent?
- Discuss quantitative analysis of steroid hormones.
- Discuss the physicochemical methods of analysis of anti-tubercular drugs and anti-malarial drugs.
- Importance of particle size analysis in dosage forms.
- Explain Carr - price reagent.
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SHORT NOTES 2 X 5 = 10 Marks
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