Download RGUHS M.Pharmacy First Year Nov 2016 9338 Biopharmaceutics And Pharmacokinetics Revised Scheme 4 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M Pharma (Master of Pharmacy) First Year (1st Year) Nov 2016 9338 Biopharmaceutics And Pharmacokinetics Revised Scheme 4 Question Paper.

Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - NOV 2016
[Time: 3 Hours] [Max. Marks: 100]
Biopharmaceutics and Pharmacokinetics
(Revised Scheme 4)
Q.P. CODE: 9338
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.

LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
1. Explain various methods to improve bioavailability of poorly water-soluble drugs.
2. Explain in detail non-per oral routes drug absorption.
3. What are the assumptions of two compartmental model? Explain two compartmental open
model with i.v bolus drug administration. Derive various pharmacokinetic parameters of the
same.

SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
4. Write about physiological Pharmacokinetic model. Comment on statistical moment theory.
5. Explain one compartment open model with extravascular drug administration along with
various pharmacokinetic parameters.
6. Explain in detail about bio equivalence study.
7. Write a note on Phase II Biotransformation reactions.
8. Describe Noyes-Whitney?s equation. Comment on similarity and dissimilarity factors.
9. Dose adjustment in renal and hepatic impairment

SHORT NOTES 2 X 5 = 10 Marks
10. Kinetics of protein binding
11. Non renal excretion of drugs

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