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Rajiv Gandhi University of Health Sciences, Karnataka
First Year M. Pharm Degree Examination – NOVEMBER 2015
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Time: Three Hours
Max. Marks: 100 Marks
CLINICAL PHARMACY PRACTICE
PAPER I
(RS2 & RS3)
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Q.P. CODE: 9261
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two)
2 x 20 = 40 Marks
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- Brief on pharmacokinetic models. Discuss on pharmacokinetic parameters like Ka, Ke, t1/2, AUC and tmax and write their significance.
- What is bioavailability? Write on design and importance of bioequivalence studies.
- Write a note on clinical trials. Give the ICH and CDSCO guidelines for the good clinical practice in the conduct of clinical trials. Discuss the various aspects of monitoring and auditing of clinical trials.
- Write on sample size calculation. Add a note on 'Chi-square' test, 't' test and 'ANOVA'. Explain the concept of "null hypothesis", "alternate hypothesis" and "degrees of freedom".
SHORT ESSAYS (Answer any FIVE)
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5 x 10 = 50 Marks
- Write in detail on pharmaceutical care plan.
- Discuss the importance and techniques of patient counseling.
- Brief on systemic approach in answering drug and poison information queries.
- Give the importance of monitoring of ADR in hospitalized patients. Add a note on spontaneous reporting system.
- Write short note on DUE & DUR.
- Explain liver function tests in its use in evaluation and diagnosis test disease states.
- Test in cardiac disorder and thyroid function tests.
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SHORT NOTES
2 x 5 = 10 Marks
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- Renal clearance.
- DUR
*****
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