Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - NOVEMBER 2015
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[Time: 3 Hours] [Max. Marks: 100]
Advanced Pharmacology and Toxicology
(Revised Scheme 4)
Q.P. CODE: 9349
Your answers should be specific to the questions asked.
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Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Write the pathophysiology, pharmacotherapy and critical analysis of rational use of drugs in asthma.
- Write the molecular mechanisms involved in cell regulation.
- Write the pathophysiology, pharmacotherapy and critical analysis of rational use of drugs in CHF.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Write the intracellular signal transduction through mitogen-activated protein kinase (MAPK) and cytokine-activated Janus kinase (JAK) / signal transducer and activator of transcription (STAT) pathway.
- Write the pathophysiology and pharmacotherapy of diabetes mellitus.
- Write a note on female reproductive toxicity.
- Write a note on in vitro tests for gene mutations in bacteria.
- Pathophysiology and pharmacotherapy of myasthenia gravis
- Pathophysiology and pharmacotherapy of peptic ulcer
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SHORT NOTES 2 X 5 = 10 Marks
- G-protein coupled receptors
- Biosynthesis of eicosanoids
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