Download RGUHS (Rajiv Gandhi University of Health Sciences) Pharm.D (Doctor of Pharmacy) 1st Semester 2014 Jan 2877 Pharmaceutical Organic Chemistry Question Paper.
Rajiv Gandhi University of Health Sciences, Karnataka
I Year Pharm. D Degree Examination ? Jan 2014
Time: Three Hours Max. Marks: 70 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. CODE: 2877
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
1. Discuss on reaction mechanism and kinetics of both the SN reaction. Elaborate the different
factors on which SN reactions depends upon.
2. Discuss on electrophillic aromatic substitution in benzene with respect to activating and
deactivating groups. Write a note on resonance stabilization of benzyl radical. Add a note on
side chain halogenation of alkyl benzene.
3. Discuss free radicals chain reactions of alkanes with mechanism in detail. Add a note on
stability of free radicals
SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks
4. Discuss the mechanism involved in theory of nitration and sulphonation.
5. Discuss the mechanism involved in Aldol and crossed Aldol condensation.
6. Discuss the mechanism involved in anti-Markownikoff?s rule
7. What is isomerism? Emphasize on keto-enol isomerism
8. Write the preparation of different acid derivatives with example.
9. Discuss 1. Phase transfer catalysis 2. Hydrogen bonding.
10. Write in detail on intermolecular forces.
11. Write the structure, assay and uses of 1. Dimercaprol 2. Saccharin sodium.
SHORT ANSWERS 10 x 2 = 20 Marks
12. Write the similarities between SN
2
and E
2
13. Write the meaning and importance of second order of reaction in reaction kinetics.
14. Nomenclature of aldehydes
15. Write some catalysts for oxidation and reduction reactions
16. Structure and uses of SLS.
17. Add a note on diazotization reaction
18. What are Carbocations? Write example
19. Write the structure of Vinyl Bromide and Allyl iodide.
20. Walden Inversion
21. Why water boiling point is more than ethanol and ethanol B.P is more than acetone?
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This post was last modified on 20 December 2019