Rajiv Gandhi University of Health Sciences, Karnataka
IV Year Pharma-D (Post Baccalaureate) Degree Examination – Mar 2013
Time: Three Hours
Max. Marks: 70 Marks
BIOSTATISTICS AND RESEARCH METHODOLOGY
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Q.P. CODE: 2870
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any two) 2 x 10 = 20 Marks
- Explain what are the different risks that can be computed in case-control and cohort studies in epidemiology?
- Explain the need for testing of hypothesis in pharmaceutical research
- Explain how computers can be made use in hospital pharmacy?
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SHORT ESSAYS (Answer any six) 6 x 5 = 30 Marks
- Discuss the advantages of computerized literature retrieval
- Define Standard deviation. The following is the waiting time (in seconds) of patients near a drugs counter in a hospital: 45, 38, 20, 29, 33, 39, 40, 37, 43, and 40 compute standard deviation
- Chi-square test
- Describe the method of drawing Scattered plots
- Write a note on SAS software
- Define null hypothesis and alternative hypothesis. On what basis do you formulate this hypothesis?
- Explain the steps involved in equality of two means using unpaired t-test.
- The following data on pulse rate was obtained from 10 individuals in a study to assess the effectiveness before and after administration of a drug:
Before: 95, 89, 98, 101, 90, 105, 110, 85, 102, 100--- Content provided by FirstRanker.com ---
After: 79, 72, 80, 75, 78, 81, 88, 73, 72, 74
Test whether the drug is effective in reducing the pulse rate after administration by stating suitable hypothesis (Critical value; 1.833)
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SHORT ANSWERS 10 x 2 = 20 Marks
- Median
- Quartiles
- Spearman's rank correlation
- Tabulation of data
- Wilcoxon signed rank test
- Semi logarithmic plots
- Variance
- Role of sample size in the calculation of standard error
- Importance of inclusion and exclusion criteria in selection of subjects in a research
- Standard error of proportion
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