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Rajiv Gandhi University of Health Sciences, Karnataka
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I Year Pharma-D Examination – Sep 2012
Time: Three Hours
Max. Marks: 70 Marks
MEDICAL BIOCHEMISTRY
Q.P. CODE: 2853
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Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
- Write in detail biochemical reactions involved in the respiration / glucose metabolism
- What is ammonia intoxication? Discuss in detail the various stages of urea cycle & give its significance
- Discuss in detail Anabolism & catabolism of fatty acids
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SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks
- Write in detail Electron Transport Chain and uncouplers of ETC
- Write examples for the following enzymatic reactions
a) Transamination (b) Deamination - Write a note on formation of Bile Pigments & give its significance
- Outline the various biochemical reactions involved in HMP shunt pathway & write its significance
- Discuss briefly various factors affecting the enzyme activity
- Outline the biosynthesis of pyrimidines
- Write briefly the process of Transcription & translation in protein synthesis
- Write in detail the significance of cyclic AMP
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SHORT ANSWERS 10 x 2 = 20 Marks
- Write the principle & methodology employed in the RIA
- What is Gluconeogenesis? Give its importance
- Differentiate between Triglycerides & Lipoproteins
- Write the therapeutic & diagnostic applications of enzymes
- What is phorphoria & Hyperbilirubinemia
- What is genetic Code? Write the base paring in any codon
- Write the principle & reactions involved in the estimation of calcium in biological samples
- Write the principle involved in the estimation of cholesterol in serum
- Give the importance of SGPT & SGOT in serum
- Write the biochemical reactions involved in the conversion of IMP to Guanine
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