Question Paper Name: Biotechnology 904 28th May 2019 Shift 2 Set 1
Subject Name: Biotechnology 904
Creation Date: 2019-05-28 18:53:25
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Duration: 180
Total Marks: 100
Display Marks: Yes
Share Answer Key With Delivery Engine: Yes
Actual Answer Key: Yes
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Biotechnology 904
Group Number: 1
Group Id: 128206113
Group Maximum Duration: 0
Group Minimum Duration: 120
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Revisit allowed for view?: No
Revisit allowed for edit?: No
Break time: 0
Group Marks: 100
PART A
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Section Id: 128206108
Section Number: 1
Section type: Online
Mandatory or Optional: Mandatory
Number of Questions: 50
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Number of Questions to be attempted: 50
Section Marks: 100
Display Number Panel: Yes
Group All Questions: No
Sub-Section Number: 1
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Sub-Section Id: 128206274
Question Shuffling Allowed: Yes
Question Number: 1 Question Id: 1282066080 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
Which among the following statements about living systems is NOT correct?
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(a) They can grow and divide
(b) They can evolve
(c) They constitute a thermodynamically closed system
(d) They can convert one form of the www.FirstRanker.com
Question Number: 2 Question Id: 1282066081 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
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Correct Marks: 2 Wrong Marks: 0
Which of the following is obtained for the reaction of 1 mole Calcium Phosphide with excess water?
(a) one mole of phosphine
(b) two moles of phosphoric acid
(c) two moles of phosphine
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(d) one mole of phosphoric acid
Options:
12820624063. A
12820624064. B
12820624065. C
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12820624066. D
Question Number: 3 Question Id: 1282066082 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
Where cross-linking of cysteine residues in polypeptides mainly occurs?
(a) inside the cell due to the reducing environment of the cytoplasm
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(b) outside of the cell due to the oxidizing environment of the extracellular medium
(c) inside the cell due to the polar environment of the cytoplasm
(d) outside of the cell due to the reducing environment of the extracellular medium
Options:
12820624067. A
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12820624068. B
12820624069. C
12820624070. D
Question Number: 4 Question Id: 1282066083 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
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If a male haemophiliac (XhY) is crossed with a female carrier of both color blindness and haemophilia (XcXh), what is the probability that a female child will be phenotypically normal?
(a) 0%
(b) 25%
(c) 50%
(d) 100%
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Options:
12820624060. B
12820624061. C
12820624062. D
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Question Number: 5 Question Id: 1282066084 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
Ten points are marked on a straight line and eleven points are marked on another straight line. How many triangles can be constructed with vertices from the above points?
(a) 495
(b) 550
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(c) 1045
(d) 2475
Options:
12820624075. A
12820624076. B
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12820624077. C
12820624078. D
Question Number: 6 Question Id: 1282066085 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
Herceptin is
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(a) a monoclonal antibody
(b) sugar binding protein produced naturally from activated T cells
(c) a drug used for juvenile diabetes
(d) DNA-protein complex
Options:
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12820624079. A
12820624080. B
12820624081. C
12820624082. D
Question Number: 7 Question Id: 1282066086 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
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Correct Marks: 2 Wrong Marks: 0
The pepscan technique is most useful for determining
(a) antibody structure
(b) discontinuous epitopes recognized by antibodies
(c) epitopes recognized by T-cells
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(d) MHC haplotypes
Options:
12820624083. A
12820624084. B
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Question Number: 8 Question Id: 1282066087 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
If you measure the ability of cytotoxic T cells from an HLA-B27 person to kill virus X-infected target cells, which one of the following statements is CORRECT?
(a) any virus X-infected target cell will be killed
(b) only virus X-infected cells of HLA-B27 type will be killed
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(c) any HLA-B27 cell will be killed
(d) no HLA-B27 cell will be killed
Options:
12820624087. A
12820624088. B
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12820624089. C
12820624090. D
Question Number: 9 Question Id: 1282066088 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
The paired t test is
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(a) impractical for large samples
(b) useful for the analysis of qualitative data
(c) useful for independent samples
(d) based on the normal distribution
Options:
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12820624091. A
12820624092. B
12820624093. C
12820624094. D
Question Number: 10 Question Id: 1282066089 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
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Correct Marks: 2 Wrong Marks: 0
Which of the following is a major enzyme that initiates the last step of complement process?
(a) C5-convertase
(b) C3-convertase
(c) C5b
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(d) C5a
Options:
12820624095. A
12820624096. B
12820624097. C
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12820624098. D
Question Number: 11 Question Id: 1282066090 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
What event of DNA virus life cycle distinguishes 'early' from 'late' viral gene expression?
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(a) expression of non-structural proteins
(b) expression of capsid proteins
(c) replication of viral genome
(d) cleavage of viral genome
Options:
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12820624099. A
12820624100. B
12820624101. C
12820624102. D
Question Number: 12 Question Id: 1282066091 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
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Correct Marks: 2 Wrong Marks: 0
What is the striking feature of transducing retroviruses?
(a) insertional activation of proto-oncogene by provirus
(b) viral genome carries cell derived oncogene
(c) infecting viral genome is intact and replication competent
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(d) tumor formation efficiency is low
Options:
12820624103. A
12820624104. B
12820624105. C
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12820624106. D
Question Number: 13 Question Id: 1282066092 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
At 12 hours of post seeding suspension cell culture, the cell density was determined to be 3.6 x 108 cells/ml. For viral infections, an aliquot of 4ml culture was withdrawn at that time and centrifuged to pellet down. If the pellet is re-suspended in 9ml medium, what is the new concentration?
(a) 16X108 cells/ml
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(b) 2X108 cells/ml
(c) 1.6X108 cell/ml
(d) 4X108 cell/ml
Options:
12820624107. A
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12820624108. B
12820624109. C
Question Number: 14 Question Id: 1282066093 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
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Which of the following nucleic acid types are not found in viruses?
(a) linear double stranded DNA
(b) circular double stranded DNA
(c) linear single stranded RNA
(d) circular single stranded RNA
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Options:
12820624111. A
12820624112. B
12820624113. C
12820624114. D
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Question Number: 15 Question Id: 1282066094 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
A-form of DNA is one of the three major structural confirmations that DNA can adopt generally under
(a) dehydrating conditions
(b) high pH conditions
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(c) high salt concentrations
(d) high potassium concentrations
Options:
12820624115. A
12820624116. B
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12820624117. C
12820624118. D
Question Number: 16 Question Id: 1282066095 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
Biochemical reaction which is not catalyzed by enzyme reverse transcriptase of retrovirus is
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(a) copying of DNA from viral DNA
(b) integration of viral genome into host genome
(c) synthesis of complementary DNA from viral RNA
(d) digestion of viral RNA in the intermediate RNA/DNA hybrid
Options:
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12820624119. A
12820624120. B
12820624121. C
12820624122. D
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Question Number: 17 Question Id: 1282066096 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
The feature that is not seen with prokaryotes in the manner in which mRNAs are produced and utilized to program translation when compared to eukaryotes
(a) the small ribosomal subunits is correctly oriented to begin translation by association with the Shine-Dalgarno sequence
(b) the 5'end of the mRNA has a methylated cap structure covalently attached after transcription
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(c) during protein synthesis an ORF can be translated by more than one ribosome forming polyribosome
(d) termination of transcription may occur at a site characterized by the formation of a GC-rich stem loop structure just upstream from a U-rich sequence
Options:
12820624123. A
12820624124. B
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12820624125. C
12820624126. D
Question Number: 18 Question Id: 1282066097 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
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student was performing gel filtration chromatography to purify an approximately 37 kDa protein using S-100, despite repeated runs, unable to separate it from proteins of higher molecular weight as shown in the following figure of the SDS-PAGE gel.
kDa M 1 2
175
83
62
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47
32 ~37 kDa
25
16
M: Protein molecular weight markers
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Lane 1: Pre-gel filtration fraction
Lane 2: Post-gel filtration fraction
The most likely reason for this could be:
(a) the column was not packed properly
(b) the high molecular weight proteins are possibly interacting with the ~37 kDa protein and therefore could not be separated, but resolved on denaturing SDS-PAGE
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(c) the resin used is not able to give good resolution and therefore the proteins are not separated and coming together
(d) not enough information to answer the question
Options:
12820624127. A
12820624128. B
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12820624129. C
12820624130. D
Question Number: 19 Question Id: 1282066098 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
To obtain a non-specific transcription from both the strands of a DNA molecule, the most efficient and effective way is to
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(a) enrich the extract with Sigma factor
(b) include the RNA holoenzyme in the reaction
(c) use the core enzyme of RNA polymerase
(d) include both the RNA holoenzyme and the core enzyme of RNA polymerase in the reaction
Options:
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12820624131. A
12820624132. C
12820624134. D
Question Number: 20 Question Id: 1282066099 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
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Correct Marks: 2 Wrong Marks: 0
Which of the following will most likely occur in a bacterial cell if the glucose level falls down?
(a) lowering of cAMP levels
(b) CAP will assist in upregulating the transcription from lac operon if lactose is added
(c) inhibition of CRP level
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(d) double strand DNA breaks
Options:
12820624135. A
12820624136. B
12820624137. C
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12820624138. D
Question Number: 21 Question Id: 1282066100 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
Which of the following is incorrect in relation to the Lac repressor involved in regulation of lac operon of E. coli.?
(a) in the absence of inducer, the repressor binds more tightly to operator DNA than to nonspecific DNA
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(b) in the presence of inducer, the repressor binds more tightly to operator DNA than to nonspecific DNA
(c) mutations in the Operator sequences are recessive
(d) mutations in the tetramerization domain are recessive
Options:
12820624139. A
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12820624140. B
12820624141. C
12820624142. D
Question Number: 22 Question Id: 1282066101 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
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lysis of replication of an organism with mutant DNA ligase at different time points after initiation of DNA replication, one would observe:
(a) the length of the DNA gradually increases in a time dependent manner till it is fully replicated
(b) there is an increase in number of small fragments with time
(c) concentration of both the small and long fragments of definite length increases with time
(d) only small fragment at first, then two separate bands showing long fragment with increasing length and short fragments of definite length
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Options:
12820624143. A
12820624144. B
12820624145. C
12820624146. D
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Question Number: 23 Question Id: 1282066102 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
The 'elongation' stage of translation, after the arrival of each new tRNA, involves:
(a) passing of the amino acid from the tRNA in the A-site to the tRNA in the P site
(b) binding of the newly arriving tRNA to the E site
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(c) passing of the peptide from the tRNA in the P site to the tRNA in the A site
(d) binding of the new tRNA to the P site of the ribosome
Options:
12820624147. A
12820624148. B
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12820624149. C
12820624150. D
Question Number: 24 Question Id: 1282066103 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
Which of the following is incorrect about beta-barrel found in proteins:
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(a) it is a type of beta sheet which twists and coils to form a closed structure in which the first strand is bonded to the last strand
(b) the strands contain alternating polar and non-polar (hydrophilic and hydrophobic) amino acids
(c) porins, preprotein translocases, lipocalins are types of beta barrels
(d) they are found only in prokaryotes cells
Options:
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12820624151. A
12820624152. B
12820624153. C
12820624154. D
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Question Number: 25 Question Id: 1282066104 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
Application of BLAST includes following except:
(a) establishing phylogeny
(b) locating domain
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(c) DNA mapping and comparison
(d) rate of speciation
Options:
12820624155. A
12820624156. B
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12820624157. C
12820624158. D
Question Number: 26 Question Id: 1282066105 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
Correct Marks: 2 Wrong Marks: 0
The learning curve is
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(a) a method to estimate adaptation to climate by microorganisms
(b) a plot of the evolution of the two error scores as training sets changes in machine learning
(c) an autocorrelation plot in cell signaling process
(d) S-shaped curve with the long lag phase in a growth curve
Options:
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12820624159. A
12820624160. B
12820624161. C
12820624162. D
Question Number: 27 Question Id: 1282066106 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
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Correct Marks: 2 Wrong Marks: 0
Support vector machine is a
(a) data mining classification algorithm in supervised machine learning model
(b) the tool to estimate the disease vector population in the outbreak area
(c) finite machine state
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(d) tool to use genetic variation
Options:
12820624163. A
12820624164. B
12820624165. C
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12820624166. D
Question Number: 28 Question Id: 1282066107 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question Option: No Option Orientation: Vertical
If the following is/are true about Fourier transformation
(a) it relates to the extraction of patterns from nature
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(b) fourier transformation, by converting data variation over time into patterns of repetition (frequency) finds hidden features
(c) can be used as tool to understand biological phenomena
(d) can be used in time dependent events only
Options:
12820624167. A
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12820624168. B
12820624169. C
12820624170. D
Question Number: 29 Question Id: 1282066108 Question Type: MCQ Option Shuffling: No Display Question Number: Yes Single Line Question
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