Download B.Pharm 2020 Feb 4th Sem Formulative Pharmacy And Bio Pharmaceutics Question Papers

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(LQ 4267) FEBRUARY 2020 Sub. Code: 4267

B.PHARM. DEGREE EXAMINATION

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FOURTH YEAR
PAPER I ? FORMULATIVE PHARMACY AND BIO-PHARMACEUTICS

Q.P. Code: 564267
Time: Three hours Maximum: 100 Marks

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I. Elaborate on: (2 x 20 = 40)

1. Define Bio-pharmaceutics. Discuss various fa ctors influencing ug
absorption in biological milieu.

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2. Explain chemical properties influe nce stability of pharmaceutical
formulation. Discuss stability testing protocol followed for biological
products.

II. Write notes on: (8 x 5 = 40)

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1. Quality control of hard gelatin capsules.
2. Process followed for bio-equivalency testing.
3. Different types of granulation techniques adopted in tablet manufacturing.
4. Sugar coating process.

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5. Nanoparticles.
6. Processing problems of tablets and its rectification.
7. Biological half-life and Elimination rate constant.
8. Multi-orifice centrifugation method used in microencapsulation.

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III. Short answers on: (10 x 2 = 20)

1. Bio availability.
2. Phase separation.
3. Bridging and filling.

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4. Different types of dissolution apparatus.
5. Compartment models.
6. Diffusion mechanism.
7. Liposomes.
8. Rat hole formation.

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9. Process variables of film coating.
10. Osmosis.

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