Download B.Pharm 2020 Feb 1st Sem Pharmaceutical Organic Chemistry Question Papers

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(LQ 4252) FEBRUARY 2020 Sub Code: 4252

B.PHARM. DEGREE EXAMINATION

FIRST YEAR

PAPER II - PHARMACEUTICAL ORGANIC CHEMISTRY

O.P. Code: 564252

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Time: Three hours Maximum: 100 Marks

I. Elaborate on: (2x20=40)

1. a) Describe Kekule structure of Benzene. Write its resonance structure of Benzene.
   b) Elaborate mechanism, kinetic, stereochemistry of Aliphatic Nucleophilic substitution reactions SN1 & SN2.
2. a) Write preparation of Alkyl halides.
   

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   b) Briefly enumerate preparation and synthetic utility of Malonic ester.
   c) Write properties of Alpha Beta unsaturated carbonyl compounds.

II. Write notes on: (8x5=40)

1. Explain Baeyer’s strain theory and its limitations.
2. Explain Markownikoffs rule.

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3. Give any five reactions of Anthracene.
4. Give preparation and medicinal uses of Saccharin.
5. Describe methods of preparation of Alcohols.
6. Explain Diels-alder reaction.
7. Write the preparation and synthetic utility of Grignard reagent.

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8. Describe mechanism of addition reaction of Conjugated dienes.

III. Short answers on: (10x2=20)

1. Define Resonance and Conjugation.
2. Draw structure of Diethyl ether and Isopropyl alcohol.
3. What are chelating agents with examples?

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4. Oxidation of primary alcohols.
5. Write two methods of synthesis of alkenes.
6. Define and classify hybridization with examples.
7. Huckel’s rule.
8. Enumerate functional derivatives of carboxylic acid.

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9. Epoxides.
10. Medicinal uses of Iodoform and Lactic acid.

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