Download PTU B.Pharmacy 2020 March 4th Sem 75845 Physical Pharmaceutics II Question Paper

Download PTU (I.K. Gujral Punjab Technical University Jalandhar (IKGPTU) ) B.Pharma (Bachelor of Pharmacy) 2020 March 4th Sem 75845 Physical Pharmaceutics II Previous Question Paper

1 M-75845 (S29)- 587

Roll No. Total No. of Pages : 02
Total No. of Questions : 13
B.Pharma (2017 Batch) (Sem.-4)
PHYSICAL PHARMACEUTICS-II
Subject Code : BP-403T
M.Code : 75845
Time : 3 Hrs. Max. Marks : 75
INSTRUCTIONS TO CANDIDATES :
1. SECTION-A is COMPULSORY consisting of TEN questions carrying TWO marks
each.
2. SECTION-B contains THREE questions carrying TEN marks each and student
has to attempt any TWO questions.
3. SECTION-C contains NINE questions carrying FIVE marks each and student has
to attempt any SEVEN questions.

SECTION-A
1. Answer briefly :
a) Colloids
b) Thixotropy and negative thixotropy
c) coacervation
d) Difference between stress and strain
e) Heckel plot is valid for which types of solids material?
f) HLB scale
g) Degree of flocculation and its units
h) Porosity
i) Ionic strength vs. degradation of pharmaceutical products
j) Arrhenious equation
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1 M-75845 (S29)- 587

Roll No. Total No. of Pages : 02
Total No. of Questions : 13
B.Pharma (2017 Batch) (Sem.-4)
PHYSICAL PHARMACEUTICS-II
Subject Code : BP-403T
M.Code : 75845
Time : 3 Hrs. Max. Marks : 75
INSTRUCTIONS TO CANDIDATES :
1. SECTION-A is COMPULSORY consisting of TEN questions carrying TWO marks
each.
2. SECTION-B contains THREE questions carrying TEN marks each and student
has to attempt any TWO questions.
3. SECTION-C contains NINE questions carrying FIVE marks each and student has
to attempt any SEVEN questions.

SECTION-A
1. Answer briefly :
a) Colloids
b) Thixotropy and negative thixotropy
c) coacervation
d) Difference between stress and strain
e) Heckel plot is valid for which types of solids material?
f) HLB scale
g) Degree of flocculation and its units
h) Porosity
i) Ionic strength vs. degradation of pharmaceutical products
j) Arrhenious equation
2 M-75845 (S29)- 587

SECTION-B
2. Discuss Principle, construction, working and applications of cone and plate viscometer.
3. Discuss Accelerated stability analysis.
4. Discuss different derived properties of powders along with their significance in
pharmacy. How they are determined or calculated?

SECTION-C
5. What is a Plug flow? Is it desirable while recording a rheogram?
6. Discuss the stability of pharmaceutical products against oxidation.
7. Explain sedimentation volume and role of flocculating agents in suspensions.
8. Discuss DLVO theory.
9. Enumerate physical factors that influencing degradation of pharmaceuticals. Discuss any
one in detail.
10. Write a note on peptization and protective action of colloids.
11. Enumerate different methods to determine particle size and discuss any one in detail.
12. A prescription for a liquid aspirin is called for, It contains 325mg/5ml or 6.5g/ 100ml.
Solubility of aspirin at 25?C is 0.33g/100ml. Therefore the suspension will definitely be a
suspension. Other ingredients in the prescription cause the product to have a pH of 6.
The first order rate constant for aspirin degradation in the solution is 4.5?10
?6
sec
?1
.
Calculate the zero order rate constant. Determine the self life, t
90
for the liquid
preparation, assuming that the product is satisfactory until at the time at which it has
decomposed to 90% of its original concentration (i.e 10% decomposition) at 25?C.
13. Calculate the HLB value of a blend of equal amounts of Polysorbate 80 and sorbitan
monooleate, the HLB values of 2 surfactants being 15 and 4.3 respectively.

NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any
page of Answer Sheet will lead to UMC against the Student.
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