Rajiv Gandhi University of Health Sciences, Karnataka
MBBS (Phase - I) Degree Examination - Dec-2014
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Time: Three Hours
Max. Marks: 100 Marks
Biochemistry — Paper I (Revised Scheme)
Q.P. CODE: 1055
Your answers should be specific to the questions asked
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Draw neat, labeled diagrams wherever necessary
LONG ESSAYS 2 x 9 = 18 Marks
- Describe Tricarboxylic Acid (Citric Acid) Cycle. Add a note on its energetics and regulation.
- Mention the sources, daily requirement, and functions of Calcium. Explain how Serum Calcium levels are regulated.
SHORT ESSAYS 10 x 5 = 50 Marks
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- Name the Co-enzyme form of Vitamin B6. Describe the biochemical reactions involving it.
- Formation and fate of Bilirubin
- Renal regulation of pH
- Write a note on Salvage pathway of Purines.
- Competitive inhibition of enzyme activity
- Explain the following aspects of Thiamine (a) Co-enzyme, (b) Functions, (c) Deficiency manifestations.
- Discuss the biochemical changes during Starvation.
- Urea cycle and its regulation
- Formation and clinical significance of Ketone bodies
- Oxidative Phosphorylation
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SHORT ANSWERS 16 x 2 = 32 Marks
- Pellagra
- Invert sugar
- Name any four diagnostic enzymes.
- Proteolytic enzymes
- Role of Carnitine in ß oxidation
- Name the enzyme defect in (a) Phenylketonuria, (b) Alkaptonuria.
- Creatinine clearance
- Respiratory Quotient
- What is Mutation? Give two examples.
- Role of Cytochrome P450 in detoxification
- Vanden Bergh’s reaction
- Name the Blood Buffers.
- Lipotropic factors
- Name the products formed from Glycine.
- Give the normal values of fasting Blood Glucose and Blood Urea.
- Hartnup’s disease
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