Rajiv Gandhi University of Health Sciences
M.B.B.S. PHASE - I Degree Examination - DECEMBER 2015
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Time: 3 Hrs. [Max. Marks: 100]
PHYSIOLOGY - PAPER I (Revised Scheme)
QP Code: 1053
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
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LONG ESSAY 2 X 9 = 18 Marks
- Describe in detail the mechanism of Antigen recognition and activation of specific immune response in both humoral and cell mediated immunity. How does HIV disease compromise immunity?
- Describe the properties of cardiac muscle.
SHORT ESSAY 10 X 5 = 50 Marks
- Describe the type of movements of large intestine and their functions.
- What is meant by Goldblatt hypertension? Explain the underlying mechanism of hypertension.
- Define renal plasma clearance of a substance. Give the formula for clearance and explain its utility in the study of renal functions.
- Describe the factors maintaining fluidity of blood in the intact vascular system and the factors favoring tendency for clot formation.
- Describe the process of fat reabsorption in the small intestine.
- Draw the diagram of left ventricular pressure-volume loop and explain the causation of component segments.
- In which type of hypoxia oxygen therapy is most helpful? What are the effects of excess oxygen administration (oxygen toxicity)?
- Describe the mode of propagation of cardiac impulse over the heart.
- Describe the composition and functions of pancreatic secretion.
- Describe the causes and treatment of decompression-sickness.
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SHORT ANSWERS 16 X 2 = 32 Marks
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- What is facultative reabsorption of water and the effect of its defect?
- What is ‘peptic ulcer’? Mention two causes for it.
- How does heparin act as an anticoagulant?
- What is Haldane effect? How is it beneficial?
- What are receptors? How are they stimulated and their reflex effects?
- Give an example of primary active transport in the cell membrane. What is its function?
- Name the bile salts and their functions.
- How and where chylomicrons are formed and their functions?
- How macrophages are derived and what are their function?
- Outline the structure of mitochondria and its function.
- What is the effect of vitamin K deficiency on coagulation?
- What is meant by filtration fraction and how is it calculated?
- Name the synthetic functions of kidney.
- Describe anaemic hypoxia.
- What is positive pressure breathing and its application?
- How is alveolar ventilation calculated? Give the formula.
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