Rajiv Gandhi University of Health Sciences, Karnataka
MBBS Phase – I Degree Examination - JULY-2018
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Time: Three Hours Max. Marks: 50 Marks
Biochemistry – Paper I (RS2 & RS3)
Q.P. CODE: 1079
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
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(Note: Both QP Codes 1079 and 1080 are to be, answered within total duration of three hours)
(Use separate Answer books for QP Code 1079 & 1080)
LONG ESSAYS 1 x 10 = 10 Marks
- Describe the formation, utilization and clinical significance of ketone bodies.
SHORT ESSAYS 5 x 5 = 25 Marks
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- Amphibolic role of citric acid cycle
- Pathway for synthesis of creatine, phosphocreatine and creatinine Clinical significance of creatinine kinase
- Outline the synthesis of cholesterol. Which is the key regulatory step
- The IUBMB classification of enzymes with one example for each class
- Different transport mechanisms across the cell membrane
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SHORT ANSWERS 5 x 3 = 15 Marks
- Metabolic abnormality and clinical manifestation of galactosemia.
- Three transmethylation reactions of S-adenosyl methionine
- Regulation of glycolysis at the phosphofructokinase step
- Energetics in the oxidation of one molecule of palmitic acid to carbon dioxide and water
- Name three tumour markers and their clinical significance
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