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Rajiv Gandhi University of Health Sciences, Karnataka
MBBS (Phase - II) Degree Examination - DEC-2014
Pharmacology - Paper I (Revised Scheme)
Time: Three Hours Max. Marks: 100 Marks Q.P. CODE: 1060
Your answers should be specific to the questions asked
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Draw neat, labeled diagrams wherever necessary
LONG ESSAYS 2 x 9 = 18 Marks
- Classify Anti-Parkinsonian drugs. Explain pharmacological actions, adverse effects and uses of levodopa.
- Classify Anti-Cholinesterases. Describe the mechanism of action and therapeutic uses of reversible anti-cholinesterases.
SHORT ESSAYS 10 x 5 = 50 Marks
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- Therapeutic uses of beta blockers
- Mechanism of action and therapeutic uses of furosemide
- Mechanism of action, therapeutic uses and adverse effects of digoxin
- Low molecular weight heparins
- Therapeutic uses and adverse effects of sodium valproate
- Advantages and disadvantages of nitrous oxide
- Transdermal patch
- Parenteral iron therapy
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SHORT ANSWERS 16 x 2 = 32 Marks
- Ketamine
- Mechanism of action and therapeutic uses of Calcium channel blockers.
- Define plasma half-life.
- Adrenaline is used in anaphylactic shock - give reason.
- Name two non-depolarizing neuromuscular blockers.
- Name four Angiotensin Converting Enzyme (ACE) inhibitors.
- Diazepam preferred over phenobarbitone as sedative - give reason.
- Define a Prodrug and give two examples.
- Morphine is contraindicated in head injury — give reason
- Pralidoxime is used in Organophosphorus poisoning — give reason.
- Name two atropine substitutes.
- Why is Propranolol contraindicated in bronchial asthma?
- Acetazolamide is used in glaucoma - give reason.
- Aspirin is contraindicated in children less than 5 years — give reason.
- Name two drugs with high first pass metabolism.
- Name two uses of nitrates.
- Name two drugs used in hypertensive emergency.
- Mention one drug used in Diabetes Insipidus with rationale.
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