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Rajiv Gandhi University of Health Sciences, Karnataka
MBBS (Phase - II) Degree Examination - DEC-2014
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Time: Three Hours Max. Marks: 100 Marks
Pharmacology – Paper I (RS2 & RS3 Scheme)
Q.P. CODE: 1085
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
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LONG ESSAYS 2 x 10 = 20 Marks
- Classify antiepileptic drugs. Describe the mechanism of antiepileptic action, therapeutic uses and adverse effects of Phenytoin Sodium.
- Describe the pharmacological actions, therapeutic uses and adverse effects of Angiotensin Converting Enzyme (ACE) inhibitors.
SHORT ESSAYS 10 x 5 = 50 Marks
- Intravenous route of drug administration
- Drug Tolerance
- Methods of prolonging duration of action of a drug
- Therapeutic uses of beta blockers
- Atropine substitutes
- Drug treatment of acute congestive glaucoma
- Chlorpromazine
- Actions of morphine on central nervous system
- Glyceryl trinitrate
- Therapeutic uses and adverse effects of Thiazide
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SHORT ANSWERS 10 x 3 = 30 Marks
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- Give the pharmacological basis for combining carbidopa with levodopa.
- Why adrenaline is combined with local anaesthetics?
- Why benzodiazepines are preferred to barbiturates as hypnotics?
- What are advantages and disadvantages of selective COX-2 inhibitors?
- Explain the basis for use of disulfiram in alcoholism.
- How do verapamil and Nifedipine differ in their cardiovascular actions?
- What is the basis for use of vasodilators in congestive heart failure?
- How does spironolactone spare potassium?
- What are advantages of low molecular weight heparins?
- Name two parenteral iron preparations. What are indications for parenteral iron therapy?
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