Rajiv Gandhi University of Health Sciences, Karnataka
MBBS (Phase - II) Degree Examination - June/July 2014
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Time: Three Hours Max. Marks: 100 Marks
Pharmacology – Paper I (RS2 & RS3 Scheme)
Q.P. CODE: 1085
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
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LONG ESSAYS 2 x 10 = 20 Marks
- Classify Anti-Parkinsonian drugs. Describe the mechanism of action, adverse effects and drug interactions of levodopa.
- Classify calcium channel blockers. Describe their pharmacological actions, therapeutic uses and adverse effects.
SHORT ESSAYS 10 x 5 = 50 Marks
- Protein binding of drug and its significance
- Factors modifying biotransformation of a drug
- Carbamazepine
- Spinal anaesthesia
- Therapeutic uses and adverse effects of benzodiazepines
- Neostigmine
- Therapeutic uses of adrenaline
- Pharmacological actions and uses of heparin
- Potassium sparing diuretics
- Pharmacological actions of organic nitrates
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SHORT ANSWERS 10 x 3 = 30 Marks
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- What are advantages and disadvantages of rectal route of drug administration?
- What are the differences between 'type A' and 'type B' of Adverse Drug Reactions?
- What are advantages of Selective Serotonin Reuptake Inhibitors (SSRI) over tricyclic antidepressant drugs?
- Name two Opioid antagonists? What are their uses?
- What is the basis for use of anticholinergics in pre-anaesthetic medication?
- What is the basis for use of Pralidoxime in Organophosphorus compound poisoning?
- How does clonidine produce its antihypertensive effect? What will happen if clonidine therapy is stopped abruptly?
- What is the basis for use of beta blockers in prophylaxis of angina?
- What are adverse effects of frusemide?
- Explain how low dose of aspirin prevents aggregation of platelets.
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