Download RGUHS B.Pharm 2020 1st Year 2628 Pharmaceutical Organic Chemistry I Rs 4 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) Bachelor of Pharmacy (B.Pharm) 2020 1st Year 2628 Pharmaceutical Organic Chemistry I Rs 4 Previous Question Paper

Rajiv Gandhi University of Health Sciences, Karnataka
I Year B. Pharm Degree Examination ? 10-Jan-2020

Time: Three Hours






Max. Marks: 70 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY ? I (RS - 4)
Q.P. CODE: 2628
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAYS (Answer any Two)
2 x 10 = 20 Marks
1. a) Discuss the mechanism and stereochemistry of SN1 reaction.
b) Explain the kinetics and mechanism of E1 reaction.
2. a) Explain the mechanism of halogenation of benzene.
b) Halogens are deactivating group but ortho & Para director. Give reasons.
3. What happens when propene is treated with hydrogen bromide? Discuss the mechanism involved
in the presence and absence of peroxide.
SHORT ESSAYS (Answer any Six)
6 x 5 = 30 Marks
4. Define with example a) Angle strain b) Huckel's rule c) Poly nuclear hydrocarbons d) Electrophiles
e) Nucleophiles.
5. What happens when isobutyl alcohol is treated with sulphuric acid? Discuss the mechanism.
6. Discuss the Bayer's strain theory with limitations.
7. Discuss allyl cation as resonance hybrid with orbital picture.
8. Outline the mechanism of Perkin's condensation.
9. Explain ionisation of carboxylic acid and write the structure of carboxylate anion.
10. Explain Cannizzaro condensation with mechanism.
11. Write the Haworth synthesis of naphthalene.
SHORT ANSWERS
10 x 2 = 20 Marks
12. What is Williamson's synthesis? Give an example.
13. Write diazotisation reaction with example.
14. Define and classify nitrenes.
15. Write the stability of carbanion.
16. Write the difference between E1 and E2 reaction.
17. What is free radical substitution reaction? Give an example
18. Classify free radicals with examples.
19. Define functional and positional isomerism with example.
20. Write the structure and IUPAC name of a) Acetic acid b) Formamide
21. Write the structure of a) Aniline b) o-cresol
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