Rajiv Gandhi University of Health Sciences, Karnataka
II Year B.Pharm Degree Examination — 14-Jan-2020
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Time: Three Hours Max. Marks: 80 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY - II
(Revised Scheme - 2)
Q.P. CODE: 1960
Your answers should be specific to the questions asked
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Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
- (a) Define polynuclear hydrocarbons. Give five examples with structure and numbering of carbon.
(b) Write the method for the synthesis of diphenyl methane. - Define and classify amino acids with examples. Write any four reactions and synthesis of amino acids.
- Give the stereochemistry of butane and cyclohexane.
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SHORT ESSAYS (Answer any Eight) 8 x 5 = 40 Marks
- Explain the stereochemical mechanism of addition of halogen to alkenes.
- What are triglycerides? Describe the significance of their iodine values.
- Why Pyrrole is more reactive than Pyridine towards electrophilic reagent?
- What are optically active compounds? Write a note on elements of symmetry.
- Give the synthesis and reactions of Phenanthrene.
- What is meant by absolute configuration? Describe the R & S system of nomenclature of optical isomers.
- Outline the method for conversion of pentose into a hexose.
- Outline two synthesis of Furan and Thiophene.
- What are fats and oils? Write a note on rancidity.
- Give Haworth’s synthesis of Naphthalene. Give its chemical properties.
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SHORT ANSWERS 10 x 2 = 20 Marks
- Define isoelectric point.
- Outline the Chichibabin reaction.
- Write the zwitter ions structure of glycine.
- Write the two synthesis of Benzofuran.
- What are aldoximes and ketoximes? Give examples.
- What are epimers? Give examples.
- How do you convert Naphthalene into 2-Nitro naphthalene?
- What is hydrogenation of oils?
- Explain with an example R & S configuration.
- Write the structures of Beta-D-Glucopyranose and Beta-D-Glucofuranose.
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